Results 61 to 70 of about 444,545 (304)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Automatic identification of simultaneous equations models [PDF]

This paper provides an operational procedure for putting indentifying restrictions on a simultaneous equations models. The algorithm works on the restrictions,not on the parameters, such that the identifying restrictions can be imposed before estimation ...
Omtzigt Pieter
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Evaluation of Two Stage Modified Ridge Estimator and Its Performance

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2018
Biasedestimation methods are more desirable than two stage least squares estimationfor simultaneous equations models suffering from the problem ofmulticollinearity.
Selma Toker, Nimet Özbay
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

SPECIES-SPECIFIC BIOMASS EQUATIONS FOR SMALL-SIZE TREE SPECIES IN SECONDARY TROPICAL FORESTS

Tropical and Subtropical Agroecosystems, 2019
Secondary tropical forests are largely dominated by small-diameter trees. Their contribution to the total stand productivity may be determinant for ecosystem functioning.
Ramiro Puc-Kauil, Gregorio Ángeles-Pérez, José René Valdez-Lazalde, Valentín José Reyes-Hernández, Juan Manuel Dupuy-Rada, Laura Schneider, Paulino Pérez-Rodríguez, Xavier García-Cuevas   +7 more
doaj  

A Gibbs simulator for restricted VAR models [PDF]

Many economic applications call for simultaneous equations VAR modeling. We show that the existing importance sampler can be prohibitively inefficient for this type of models.
Daniel F. Waggoner, Tao Zha
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Mathematical Modeling and Simulation of the Dehydrogenation of Ethyl Benzene to Form Styrene Using Steady-State Fixed Bed Reactor

Tikrit Journal of Engineering Sciences, 2013
In this research, two models are developed to simulate the steady state fixed bed reactor used for styrene production by ethylbenzene dehydrogenation. The first is one-dimensional model, considered axial gradient only while the second is two-dimensional ...
Zaidon M. Shakoor
doaj  

ANALISIS HUBUNGAN ANTARA KETERSEDIAAN PUSAT INFORMASI DAN INTENSITAS PUBLIKASI KEGIATAN WISATA TERHADAP KONTRIBUSI EKONOMI SEKTOR PARIWISATA

J@ti Undip: Jurnal Teknik Industri, 2012
Penelitian ini ditujukan untuk menganalisis hubungan antara ketersediaan pusat informasi dan intensitas publikasi kegiatan wisata terhadap Kontribusi Ekonomi Sektor Pariwisata.
Wahyudi Sutopo
doaj   +1 more source