Results 121 to 130 of about 475,022 (324)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Determination of the conductivity and thickness of conductive layers on conductive base materials

open access: yesAdvances in Mechanical Engineering, 2019
An eddy current technique for the simultaneous determination of the layer thickness and conductivity of a uniform conductive layer on a known conductive base material is presented.
John Burkhardt
doaj   +1 more source

Twin-Core Fiber-Based Mach Zehnder Interferometer for Simultaneous Measurement of Strain and Temperature

open access: yesSensors, 2018
In this paper we present an all-fiber interferometric sensor for the simultaneous measurement of strain and temperature. It is composed of a specially fabricated twin-core fiber spliced between two pieces of a single-mode fiber.
Dominik Kowal   +2 more
doaj   +1 more source

Analysis of a Very Massive DA White Dwarf via the Trigonometric Parallax and Spectroscopic Methods

open access: yes, 2003
By two different methods, we show that LHS 4033 is an extremely massive white dwarf near its likely upper mass limit for destruction by unstable electron captures.
Bergeron, P.   +4 more
core   +2 more sources

Simultaneous segmentation and bias field estimation using local fitted images

open access: yesPattern Recognition, 2018
Level set methods often suffer from boundary leakage and inadequate segmentation when used to segment images with inhomogeneous intensities. To handle this issue, a novel region-based level set method was developed, in which two different local fitted images are used to construct a hybrid region intensity fitting energy functional.
Lei Wang 0163   +5 more
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A comparison of sLASER and MEGA-sLASER using simultaneous interleaved acquisition for measuring GABA in the human brain at 7T.

open access: yesPLoS ONE, 2019
γ-Aminobutyric acid (GABA), the major inhibitory neurotransmitter, is challenging to measure using proton spectroscopy due to its relatively low concentration, J-coupling and overlapping signals from other metabolites.
Donghyun Hong   +4 more
doaj   +1 more source

Measurement of Planetary Boundary Layer Winds with Scanning Doppler Lidar

open access: yesRemote Sensing, 2018
The accurate measurement of wind profiles in the planetary boundary layer (PBL) is important not only for numerical weather prediction, but also for air quality modeling.
Soojin Park   +3 more
doaj   +1 more source

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