Results 31 to 40 of about 9,921 (254)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Weighted Sum Transmit Power Minimization for Full-Duplex System With SWIPT and Self-Energy Recycling

IEEE Access, 2016
This paper considers a full-duplex (FD) point-to-point system consisting of one multi-antenna FD access point (FD-AP) and one two-antenna FD mobile station (FD-MS).
Zhongwei Hu, Chaowei Yuan, Fengchao Zhu, Feifei Gao   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Beamforming Design for Full-Duplex SWIPT with Co-Channel Interference in Wireless Sensor Systems

Sensors, 2018
The simultaneous wireless information and power transfer (SWIPT) technique has been regarded as an appealing approach to prolong the lifetime of wireless sensor networks.
Xiaoqing Liu, Yinglin Jia, Zhigang Wen, Junwei Zou, Shan Li   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A Tri-Port SIW STAR Antenna With Independent Resonance Control and Self-Interference Suppression for UAV Full-Duplex Communication

IEEE Access
This paper presents a tri-port substrate integrated waveguide (SIW) STAR antenna with independent resonance control and antenna-layer self-interference suppression for uncrewed aerial vehicle (UAV) full-duplex communication systems.
Durga Prasad Purbey, Sandip Ghosal, Arijit De, Abhishek Sarkhel   +3 more
doaj   +1 more source

MIMO Codes for Uniform Illumination Across Space and Time in VLC With Dimming Control

IEEE Photonics Journal, 2019
Indoor visible light communications (VLC) require simultaneous illumination and communication. Hence, uniformity in the illumination is a key consideration for user comfort and data transfer in the VLC systems.
Uday Thummaluri, Abhinav Kumar, Lakshmi Natarajan   +2 more
doaj   +1 more source