Results 191 to 200 of about 11,999,664 (286)

Protein Tyrosine Phosphatase 1B‐Mediated Granulosa Cell Insulin Resistance Links Metabolic Stress to Aging‐Relevant Ovarian Dysfunction and Is Reversed by Gengnianchun

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Metabolic stress induces insulin resistance and upregulates PTP1B in granulosa cells, leading to aging‐relevant ovarian dysfunction. Gengnianchun (GNC) suppresses PTP1B, restores IRS1–AKT2–GLUT4 signaling, and preserves follicles, highlighting PTP1B as a therapeutic target for ovarian dysfunction in metabolically vulnerable states.
Yanqiu Rao   +6 more
wiley   +1 more source

ALKBH5 facilitates Srgn stability via m6A demethylation to disrupt blood-testis barrier integrity in the high-fat diet mice. [PDF]

open access: yesCell Mol Life Sci
Du T   +17 more
europepmc   +1 more source

RNA Metabolism Genes as Prognostic Biomarkers and Therapeutic Targets in Colorectal Cancer Based on the Analysis of Single‐Cell and Bulk‐RNA Sequencing Data

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT Colorectal cancer (CRC) is one of the most common malignancies worldwide and remains a major cause of cancer‐related mortality. Increasing evidence suggests that aberrant RNA metabolism contributes to tumour initiation, progression and therapeutic resistance.
Fandong Kong   +6 more
wiley   +1 more source

Enhanced Enzyme Cascade Reactions Through Coencapsulation in Biocompatible Silica Nanoconfinement

open access: yesChemBioChem, Volume 27, Issue 10, 27 May 2026.
We coencapsulated glucose oxidase (GOX) and horseradish peroxidase (HRP) within silica nanoconfinement using an enzyme‐friendly synthesis method. The coencapsulated system demonstrated faster cascade kinetics than spatially separated configurations, providing direct evidence for beneficial proximity effects on intermediate transfer.
Ji‐Soo Lee   +10 more
wiley   +1 more source

On sampling series based on some combinations of sinc functions

open access: yesProceedings of the Estonian Academy of Sciences. Physics. Mathematics, 2002
Kivinukk, Andi, Tamberg, Gert
openaire   +2 more sources

Mutant p53 binds and controls estrogen receptor activity to drive endocrine resistance in ovarian cancer. [PDF]

open access: yesGenes Dev
Shao C   +14 more
europepmc   +1 more source

Resonance Energy Transfer-Driven Photothermal Nanoagent Enables Melanoma Ablation Under Low-Power Near-Infrared Irradiation. [PDF]

open access: yesAdv Funct Mater
Singh P   +16 more
europepmc   +1 more source

Hybrid ray-tracing-QuaDRiGa/FDTD method for realistic 28 GHz exposure with 6G CF-MaMIMO in 3D outdoor environments. [PDF]

open access: yesNPJ Wirel Technol
Wydaeghe R   +5 more
europepmc   +1 more source

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