Results 71 to 80 of about 399,638 (284)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

A Cluster Expansion for Dipole Gases

, 1998
We give a new proof of the well-known upper bound on the correlation function of a gas of non-overlapping dipoles of fixed length and discrete orientation working directly in the charge representation, instead of the more usual sine-Gordon representation.
Frohlich, J.Rodrigo Parreira, Marchetti, Oscar Bolina   +3 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Fourth-Order Hankel Determinants and Toeplitz Determinants for Convex Functions Connected with Sine Functions

Journal of Mathematics, 2022
This article deals with the upper bound of fourth-order Hankel and Toeplitz determinants for the convex functions which are defined by using the sine function.
Farah Zulfiqar, Sarfraz Nawaz Malik, Mohsan Raza, Md. Shajib Ali   +3 more
doaj   +1 more source

Towards the Construction of Wightman Functions of Integrable Quantum Field Theories

, 2004
The purpose of the ``bootstrap program'' for integrable quantum field theories in 1+1 dimensions is to construct a model in terms of its Wightman functions explicitly.
Babujian H., Babujian H., Babujian H., Babujian H. M., Berg B., Brazhnikov V., Coleman S., Delfino G., Fateev V. A., H. BABUJIAN, Karowski M., Karowski M., Karowski M., Karowski M., Karowski M., Kosterlitz J. M., Koubek A., LeClair A., Lukyanov S., M. KAROWSKI, Mussardo G., Schroer B., Schroer B., Smirnov F. A., Smirnov F. A., Vergeles S., Weisz P., Yurov V. P., Zamolodchikov A. B., Zamolodchikov A. B., Zamolodchikov Al. B.   +30 more
core   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Optimal parameters for fiber Bragg gratings for sensing applications: a spectral study

SN Applied Sciences, 2021
The spectral characteristics viz. reflectivity, bandwidth, and sidelobes’ intensity for uniform and apodized (Gaussian, hyperbolic tangent, apod1, sine, and raised sine) fiber Bragg gratings (FBGs) were studied as a function of grating length and index ...
P. V. Raja Shekar, D. Madhavi Latha, Kusum Kumari, V. G. K. M. Pisipati   +3 more
doaj   +1 more source

Quantization of Sine-Gordon solitons on the circle: semiclassical vs. exact results

, 2008
We consider the semiclassical quantization of sine-Gordon solitons on the circle with periodic and anti-periodic boundary conditions. The 1-loop quantum corrections to the mass of the solitons are determined using zeta function regularization in the ...
Arscott, Bazhanov, Bordag, Bordag, Braden, Braden, Dashen, Dashen, Destri, Dorey, Erdélyi, Feverati, Feverati, Kirsten, Kirsten, Kirsten, Kohn, Lüscher, Makhanov, Michael Pawellek, Mussardo, Mussardo, Neveu, Novikov, Pawellek, Rajaraman, Smirnov, Turbiner, Voros, Whittaker, Zamolodchikov   +30 more
core   +1 more source