Results 181 to 190 of about 2,277,000 (297)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Rate-Dependent Hysteresis Modeling and Hybrid Inverse Compensation Control for Piezoelectric Actuators. [PDF]

Sensors (Basel)
Guo Q, Yu Z, Zhou J.
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Construction method and performance analysis of chaotic frequency-hopping sequences based on Logistic-Sine-Cosine mapping

Tongxin xuebao
In order to solve the problems of low dimensional chaotic mapping, limited chaotic behavior, and discontinuous chaotic interval, a new construction method of chaotic frequency-hopping sequence was proposed.
CAO Chunjie, WANG Yinglin, SUN Yang, TAO Hongfei, YANG Haoning, SHI Jingcheng, DAI Junhao, SUN Jingzhang   +7 more
doaj  

AINR: attention-guided implicit neural representations for spatial domain identification in spatial transcriptomics. [PDF]

Bioinform Adv
Zhang Y, Xiao G, Li P, Liu J.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Cortical representation of pitch perception in mice. [PDF]

Commun Biol
Putnam JW, Kumar A, Gill NK, Dinh J, Orellana Castellanos F, Leusch S, Vaughn S, Francis NA.   +7 more
europepmc   +1 more source

Map of the city of Melbourne [cartographic material] : including the municipalities of Emerald Hill & Collingwood ... /

Map 282 from Ferguson Collection.; Map shows streets, railways, buildings, parks and reserves, and names wards.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map-f282; Library copy folded to 16.8 x 11.5 ...
Mason, Cyrus, 1830-1915.
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source