Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity
Advanced Science, EarlyView.This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley +1 more source
\u27Sing to the Lord a New Song\u27: The Regular Singing Movement in Colonial New England
, 2004 “Outward Melody in Religious Singing is no small Help to inward Devotion. In this our imbodyd [sic] State the Senses do very strongly impress the superior Power of the Mind; especially the Ear and Eye do variously affect the Heart.” Cotton Mather penned ...
Farrer, Katie
core
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Haydn's Welsh songs: George Thomson's musical and literary sources / Caneuon Cymreig Haydn: Ffynonellau Cerddorol a Llenyddol George Thomson [PDF]
, 2008 No abstract ...
Rycroft, M.
core
K-pop Lyric Translation: Dataset, Analysis, and Neural-Modelling
, 2023 Lyric translation, a field studied for over a century, is now attracting computational linguistics researchers. We identified two limitations in previous studies.
Jeong, Dasaem +3 more
core
Advanced Science, EarlyView.ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan +12 more
wiley +1 more source
What Happens When an Invented Language Is Set To Music?: A Linguistic Study of Dogorian [PDF]
, 2010 Dogora, suite populaire dogorienne de Proszeshny orientale, composed by Etienne Perruchon and adapted for cinema by director Patrice Leconte, sets 'le dogorien' (referred to here as Dogorian), an 'imaginary language' created by the composer, to music ...
Arleo, Andy
core +2 more sources
Toma de decisiones en la traducción de canciones: una visión de la traducción al español de la canción de David Bowie «Space Oddity» [PDF]
, 2019 Theoretical background on the topic of ‘song translation’ shows complexity in the approach and difficulty in achieving solid singable translations, particularly in canonized songs, without reducing their original values.
Barberá Ubeda, José Manuel
core +2 more sources
Advanced Science, EarlyView.An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He +28 more
wiley +1 more source
Song and dance: a memetic angle on the evolution of musicality and music via case studies of a musemeplex in Saint-Saëns and ABBA. [PDF]
Front Psychol, 2023 Jan S.
europepmc +1 more source