Results 91 to 100 of about 524,098 (315)

Miniaturized Bidirectional Thermal Stimulation System Integrated With an Electrode Array for Recording Neural Activities

open access: yesAdvanced Science, EarlyView.
This study presents a miniaturized bidirectional thermal stimulation system integrated with an electrode array enabling real‐time, bidirectional modulation and simultaneous recording of neural activity through localized heating and cooling. By monolithic integration of the Peltier element and with a silicon neural probe, the innovative system allows ...
Zoia Naumkina   +6 more
wiley   +1 more source

The responsibilities of lawyers for their clients misstatements and omissions to the securities market in Singapore

open access: yes, 2014
Ministry of Education, Singapore under its Academic Research Funding Tier
WAN, Wai Yee
core  

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

open access: yesAdvanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou   +21 more
wiley   +1 more source

Obesity in Singapore

open access: yesAnnals of the Academy of Medicine, Singapore, 2001
The word obesity implies an excess of adipose tissue (fat) and not merely an excess of body weight. An increase in body weight may be due to fat (as in an obese person) or due to lean muscles (as in Hercules or in a body builder).
openaire   +3 more sources

Where judicial and legislative powers conflict: Dealing with legislative gaps (and non-gaps) in Singapore

open access: yes, 2016
Ministry of Education, Singapore under its Academic Research Funding Tier
GOH, Yihan
core  

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

Freshwater fishes, terrestrial herpetofauna and mammals of Pulau Tekong, Singapore

open access: yes, 2016
The diversity of terrestrial and freshwater, non-avian, vertebrate fauna of Pulau Tekong, an island used almost exclusively by the Singapore Armed Forces, was compiled.
Lim, Norman (Norman T-Lon)   +2 more
core  

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

On the Topography of Singapore [PDF]

open access: yesThe American Journal of the Medical Sciences
n ...
openaire   +2 more sources

Managing Mens Rea in Singapore

open access: yes, 2006
This article looks at some of the most important issues surrounding the requirement of mens rea in Singapore criminal law today. The purpose is to measure the state of its health. It concludes that, although not all developments in recent years have been
Hor, MYM
core  

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