Results 151 to 160 of about 3,551,300 (318)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Epstein-Barr Virus Infection at Single-Cell Resolution. [PDF]
J Med VirolSoRelle ED.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Current landscape of single-cell genomics in meningioma. [PDF]
Neurooncol AdvEllenbogen Y +7 more
europepmc +1 more source
Physiological functions and regulation of K+ and Cl- channels in single smooth muscle cells.
, 1993 Yuji Imaizumi +3 more
openalex +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Raman Spectral Signatures of Human Neutrophils: A Single-Cell Approach. [PDF]
J BiophotonicsVaňková L +4 more
europepmc +1 more source