Results 251 to 260 of about 3,551,300 (318)

A Practical Approach to Study Uncultivated Protists Using Single-Cell Techniques for Electron Microscopy. [PDF]

J Eukaryot Microbiol
Palka MV, Wakeman KC, Park E, Lax G, Leander BS.   +4 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Brain Single-Cell Transcriptional Responses to Bexarotene-Activated RXR in an Alzheimer's Disease Model. [PDF]

Int J Mol Sci
Saibro-Girardi C, Lu Y, Fitz NF, Gelain DP, Lefterov I, Koldamova R.   +5 more
europepmc   +1 more source

Single-cell RT-PCR Analysis and CRF Effects on TRPC Channels Expressed in Rat Brain

, 2011
Nicole M. Jones
openalex  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

A single-cell cytokine dictionary of human peripheral blood

Theis F, Oesinghaus L, Becker S, Vornholz L, Papalexi E, Pangallo J, Moinfar A, Liu J, Fleur AL, Shulman M, Marrujo S, Hariadi B, Curca C, Suyama A, Nigos M, Sanderson O, Nguyen H, Tran V, Sapre A, Kaplan O, Schroeder S, Salvino A, Gallareta-Olivares G, Koehler R, Geiss G, Rosenberg A, Roco C, Seelig G.   +27 more
europepmc   +1 more source

Pitfalls in analysis and interpretation of single-cell RNA-seq data in cancer. [PDF]

Neurooncol Adv
Tirosh I.
europepmc   +1 more source

Immune tolerance dissected by single-cell transcriptomics

, 2017
Ricardo J. Miragaia
openalex   +1 more source

eLife Assessment: Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

Fabienne Lescroart
openalex   +1 more source

Research Progress of Interstitial Lung Disease Based on Single-Cell Sequencing Technology. [PDF]

Can Respir J
Li S, Zhou T, Zhang J, Zhang L, Li Q, Li B, Dai J, Yu R, Li Y, Li S.   +9 more
europepmc   +1 more source