Results 131 to 140 of about 4,737,492 (306)

Cell cycle analysis of primary sponge cell cultures

, 2011
Proliferation of sponge cells is generally measured via cell counts or viability assays. However, more insight into the proliferative state of a sponge cell population can be obtained from the distribution of the cells over the different phases of the ...
Pomponi, S.A., Dirk E. Martens, Shirley A. Pomponi, Klaske J. Schippers, Martens, D.E., Schippers, K.J., Wijffels, R.H., René H. Wijffels   +7 more
core   +1 more source

Kernel-based testing for single-cell differential analysis

Genome Biology
Single-cell technologies offer insights into molecular feature distributions, but comparing them poses challenges. We propose a kernel-testing framework for non-linear cell-wise distribution comparison, analyzing gene expression and epigenomic ...
A. Ozier-Lafontaine, C. Fourneaux, G. Durif, P. Arsenteva, C. Vallot, O. Gandrillon, S. Gonin-Giraud, B. Michel, F. Picard   +8 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

seandavi/awesome-single-cell: 2017-12-18-1

, 2017
List of software packages for single-cell data analysis, including RNA-seq, ATAC-seq ...
Patrick Roelli, Mustafa Anil Tuncel, Joshua Welch, Fabio Zanini, Poirion olivier, Olga Botvinnik, Debajyoti Sinha, Luke Zappia, John Reid, Peter Hickey, Beate Vieth, Yun YAN, Robert Aboukhalil, Vladimir Kiselev, Rintu Kutum, AlessandraDM, MikeDMorgan, Nathan Salomonis, Vincent Gardeux, Charlotte Soneson, Kieran R Campbell, Aris Floratos, David DeTomaso, Catalina Vallejos, Alex Wolf, Sean Davis, Anthony Gitter, Dakota Hawkins, Michael Kelly, Keegan Korthauer   +29 more
core   +1 more source

THE ANALYSIS OF SINGLE CELLS

Journal of Biological Chemistry, 1956
M L, CHANG, O H, LOWRY, N R, ROBERTS
openaire   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Single Cell Analysis of Human RAD18-Dependent DNA Post-Replication Repair by Alkaline Bromodeoxyuridine Comet Assay

, 2013
Damage to DNA can block replication progression resulting in gaps in the newly synthesized DNA. Cells utilize a number of post-replication repair (PRR) mechanisms such as the RAD18 controlled translesion synthesis or template switching to overcome the ...
Himabindu Gali, Mórocz Mónika, Downes C. Stephen, Raskó István, Haracska Lajos, Downes, C. Stephen, Gali Himabindu, C Stephen Downes, Mórocz, Mónika, Lajos Haracska, Mónika Mórocz, Gali, Himabindu, Raskó, István, Haracska, Lajos, István Raskó   +14 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Integrated Single-Cell and Spatial Transcriptomic Analysis Identifies ISR-Related Genes Driving Immune Regulation in Parkinson’s Disease

Journal of Inflammation Research
Hua Jiang,1 Xiaotian Zhang,2,3 Shengyu Feng,2,3 Wei Feng2,3 1Clinical Laboratory, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Anesthesiology, The Affiliated Hospital of Qingdao University ...
Jiang H, Zhang X, Feng S, Feng W
doaj