Results 151 to 160 of about 3,157,298 (256)

Single-cell analysis reveals essential lncRNAs regulating human trophoblast lineage differentiation. [PDF]

Life Med
Zhang W, Le C, Yi S, Liu W, Liu X, Yin Z, Wang H, Gao R, Gao S, Chen J.   +9 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Single-cell analysis and control of microbial systems using optogenetics. [PDF]

Curr Opin Microbiol
Huang H, Dunlop MJ.
europepmc   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Protocol for retinal stress culture and single-cell analysis. [PDF]

STAR Protoc
Norrie JL, Ramirez C, Dyer MA.
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS. [PDF]

J Neuroinflammation
Falk S, Krämer J, Leson S, Pilo D, Deffner M, Ostkamp P, Lu IN, Schneider-Hohendorf T, Schulte-Mecklenbeck A, Wünsch C, Gross CC, Steinbrink K, Bischof A, Korsukewitz C, Meyer Zu Hörste G, Klotz L, Weishaupt C, Wiendl H, Schwab N.   +18 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Single-Cell Analysis of Preeclamptic Cord Blood Mononuclear Cells Revealed Activation of Heme-Associated Signalling Pathways. [PDF]

J Cell Mol Med
Vishnyakova P, Karpulevich E, Karyagina V, Gantsova E, Trofimovich Y, Kiseleva V, Chirkova M, Gerashchenko T, Lokhonina A, Muminova K, Khodzhaeva Z, Denisov E, Elchaninov A, Fatkhudinov T, Sukhikh G.   +14 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source