Topology‐Aware Deep Learning on Higher‐Order Structures for Drug Response Prediction
We present TopDr, a topology‐aware deep learning framework that encodes both drugs and cell lines as multiscale simplicial complexes, capturing interactions at the 0‐, 1‐, and 2‐simplex levels. By jointly integrating local higher‐order neighborhoods and global topological structures, TopDr generates enriched representations for sensitivity prediction ...
Cong Shen +3 more
wiley +1 more source
Neuromodulation of Working Memory: Mechanisms, Targets, and Behavioral Outcomes. [PDF]
Sadat Rafiei SK +7 more
europepmc +1 more source
Thermodynamic prediction of RNA cellular activity from sequence via conformational ensembles. [PDF]
Geng A +12 more
europepmc +1 more source
Heutagogy: A Comprehensive Review of Self-Determined Learning in Contemporary Education. [PDF]
Panta R.
europepmc +1 more source
Priming iTBS for lower limb rehabilitation after stroke: Protocol for a randomized controlled trial on efficacy and neuroplasticity. [PDF]
Pan Z +13 more
europepmc +1 more source
Techniques for mitigating overfitting in machine learning: a comprehensive review, taxonomy, and practical guide. [PDF]
Sheppert AP.
europepmc +1 more source
MetaComb: a meta-learning framework for drug combination response prediction from cell lines to patients. [PDF]
Guo C +8 more
europepmc +1 more source
Related searches:
Action Learning, Fragmentation, and the Interaction of Single-, Double-, and Triple-Loop Change
The Journal of Applied Behavioral Science, 1999The action-learning framework is traditionally used to summarize complex change efforts as one of three methods: single-, double-, or triple-loop. Although this summary is quite useful for some kinds of organizational analysis, it can oversimplify and thus ignore the fragmented, contradictory nature of change.
Erica Gabrielle Foldy +1 more
openaire +3 more sources

