Results 111 to 120 of about 1,476,983 (297)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Learning Single Index Models in High Dimensions

open access: yesCoRR, 2015
16 pages, 2 figures, 1 ...
Ravi Ganti   +3 more
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Longitudinal image-based prediction of surgical intervention in infants with hydronephrosis using deep learning: Is a single ultrasound enough?

open access: yesPLOS Digital Health
The potential of deep learning to predict renal obstruction using kidney ultrasound images has been demonstrated. However, these image-based classifiers have incorporated information using only single-visit ultrasounds.
Adree Khondker   +12 more
doaj   +1 more source

A Sequential Approach to the Biodynamic Modeling of a Human Finger

open access: yesShock and Vibration, 2017
In an effort to understand the vibration-induced injuries incurred by manual workers, mechanical models are developed and used to predict the biodynamic responses of human body parts that are exposed to vibration.
Luka Knez, Janko Slavič, Miha Boltežar
doaj   +1 more source

Endogeneity in semiparametric binary response models

open access: yes, 2003
This paper develops and implements semiparametric methods for estimating binary response (binary choice) models with continuous endogenous regressors. It extends existing results on semiparametric estimation in single index binary response models to the ...
Blundell, R., Powell, J.L.
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

MODELING OF EXTRUSION PROCESS USING RESPONSE SURFACE METHODOLOGY AND ARTIFICIAL NEURAL NETWORKS [PDF]

open access: yesJournal of Engineering Science and Technology, 2006
Artificial neural networks are a powerful tool for modeling of extrusion processing of food materials. Wheat flour and wheat– black soybean blend (95:5) were extruded in a single screw Brabender extruder with varying temperature (120 and 140 oC), dry ...
NEELAM SHIHANI   +2 more
doaj  

Genomic Prediction Accounting for Genotype by Environment Interaction Offers an Effective Framework for Breeding Simultaneously for Adaptation to an Abiotic Stress and Performance Under Normal Cropping Conditions in Rice

open access: yesG3: Genes, Genomes, Genetics, 2018
Developing rice varieties adapted to alternate wetting and drying water management is crucial for the sustainability of irrigated rice cropping systems. Here we report the first study exploring the feasibility of breeding rice for adaptation to alternate
Manel Ben Hassen   +4 more
doaj   +1 more source

Simple models and the corresponding h- and g-index [PDF]

open access: yes, 2006
The relation between the Hirsch index and Egghe’s g-index is determined for some simple models such as the uniform model, the point model, the linear model and Zipf’s ...
Rousseau, Ronald
core  

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