Results 111 to 120 of about 6,439,042 (312)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Large mode area fibers are imperative for scaling up the average power of fiber lasers. Single-mode behavior and low FM loss are the crucial functionalities for these fibers.
Baskiotis, C. +3 more
core +1 more source
Wang-Single-mode sapphire fiber Bragg grating Fig7d.csv
, 2022 "Single-mode sapphire fiber Bragg grating" Data File 5 (Underlying data for Figure 7d) Measured reflection spectrum of a sapphire waveguide Bragg ...
Frank Payne (11688151) +6 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Numerical solution of single mode gyrotron equation
Mathematical Modelling and Analysis, 2004 In this paper we study numerical problems arising in solving the single mode gyrotron equation. Using the method of finite differences analytical and numerical solutions are obtained.
O. Dumbrajs, H. Kalis, A. Reinfelds
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
High Polarization Single Mode Photonic Crystal Microlaser
, 2009 Generally, dipole mode is a doubly degenerate mode. Theoretical calculations have indicated that the single dipole mode of two-dimensional photonic crystal single point defect cavity shows high polarization property. We present a structure with elongated
Zhou WJ +5 more
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Numerical experiments with single mode gyrotron equations
Mathematical Modelling and Analysis, 2012 Gyrotrons are microwave sources whose operation is based on the stimulated cyclotron radiation of electrons oscillating in a static magnetic field. This process is described by the system of two complex differential equations: nonlinear first order ...
Andrejs Reinfelds +4 more
doaj +1 more source