Results 91 to 100 of about 167,152 (283)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Possible origin of thermoelectric response fluctuations in single-molecule junctions

New Journal of Physics, 2013
The thermoelectric response of molecular junctions exhibits large fluctuations, as observed in recent experiments (e.g. Malen J A et al 2009 Nano Lett. 10 3406).
Yonatan Dubi
doaj   +1 more source

Vibrationally coupled electron transport in single-molecule junctions: The importance of electron-hole pair creation processes

, 2013
Vibrationally coupled electron transport through single-molecule junctions is considered. Reviewing our recent theoretical work, we show that electron-hole pair creation processes represent the key to understand the vibrational excitation characteristic ...
Arroyo, Avriller, Ballmann, Ballmann, Benesch, Benesch, Benesch, Bergfield, Bergfield, Boese, Broekaert, Böhler, Cederbaum, Cizek, Davies, Davies, Elbing, Evers, Galperin, Galperin, Galperin, Groshev, Guedon, Herrmann, Härtle, Härtle, Härtle, Härtle, Härtle, Härtle, Härtle, Hüttel, Keane, Kießlich, Kim, Koch, Lüffe, Mathews, Mazumder, Meir, Mitra, Mujica, Osorio, Osorio, Pascual, Persson, Romano, Sapmaz, Schulze, Secker, Solomon, Stafford, Tao, Volkovich, Wang, Ward, Xue, Zazunov   +57 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Electron-vibration interaction in single-molecule junctions: from contact to tunneling regime [PDF]

, 2008
Point contact spectroscopy on a H2O molecule bridging Pt electrodes reveals a clear crossover between enhancement and reduction of the conductance due to electron-vibration interaction.
B. Leerink, I. K. Yanson, I. K. Yanson, J. M. van Ruitenbeek, M. Krieger, O. Tal, R. Landauer   +6 more
core   +3 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Electrical monitoring of single-event protonation dynamics at the solid-liquid interface and its regulation by external mechanical forces

Nature Communications
Detecting chemical reaction dynamics at solid-liquid interfaces is important for understanding heterogeneous reactions. However, there is a lack of exploration of interface reaction dynamics from the single-molecule perspective, which can reveal the ...
Cong Zhao, Jiazheng Diao, Zhao Liu, Jie Hao, Suhang He, Shaojia Li, Xingxing Li, Guangwu Li, Qiang Fu, Chuancheng Jia, Xuefeng Guo   +10 more
doaj   +1 more source

Vibronic effects on resonant electron conduction through single molecule junctions

, 2006
The influence of vibrational motion on electron conduction through single molecules bound to metal electrodes is investigated employing first-principles electronic-structure calculations and projection-operator Green's function methods.
Benesch, C., Cizek, M., Domcke, W., Thoss, M.   +3 more
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Total variation denoising-based method of identifying the states of single molecules in break junction data

Discover Nano
Break junction (BJ) measurements provide insights into the electrical properties of diverse molecules, enabling the direct assessment of single-molecule conductances.
Yuki Komoto, Jiho Ryu, Masateru Taniguchi   +2 more
doaj   +1 more source