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Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Clinical Spectrum and Outcomes of SOX1 Antibody‐Associated Paraneoplastic Neurological Syndromes: A Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background SOX1 antibody‐positive paraneoplastic neurological syndromes (PNS) exhibit significant population‐specific clinical heterogeneity. While Western cohorts predominantly manifest Lambert‐Eaton myasthenic syndrome (65%–80%), comprehensive clinical characterization and treatment response data in Asian populations remain critically ...
Jin‐Long Ye   +11 more
wiley   +1 more source
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Reactions in single-molecule junctions

Nature Reviews Materials, 2022
Hongliang Chen   +2 more
exaly   +2 more sources

Radical Single-Molecule Junctions

Journal of the American Chemical Society, 2023
Radicals are unique molecular systems for applications in electronic devices due to their open-shell electronic structures. Radicals can function as good electrical conductors and switches in molecular circuits while also holding great promise in the field of molecular spintronics.
Liang Li   +4 more
openaire   +2 more sources

Single-Molecule Junction Formation in Break-Junction Measurements

The Journal of Physical Chemistry Letters, 2021
The scanning tunneling microscope-based break-junction (STM-BJ) technique is the most common method used to study the electronic properties of single-molecule junctions. It relies on repeatedly forming and rupturing a Au contact in an environment of the target molecules.
Tianren Fu   +3 more
openaire   +2 more sources

Fano Resonance in Single‐Molecule Junctions

Angewandte Chemie, 2022
AbstractThe Fano resonance in single‐molecule junctions could be created by interaction with discrete and continuous molecular orbitals and enables effective electron transport modulation between constructive and destructive interference within a small energy range.
Yan Zheng   +16 more
openaire   +2 more sources

Plasmon Squeezing in Single-Molecule Junctions

Nano Letters, 2022
Scanning tunneling microscope (STM)-induced luminescence provides an ideal platform for electrical generation and the atomic-scale manipulation of nonclassical states of light. However, despite its extreme importance in quantum technologies, squeezed light emission with reduced quantum fluctuations has hitherto not been demonstrated in such a platform.
Lei-Lei Nian, Tao Wang, Jing-Tao Lü
openaire   +2 more sources

SINGLE-MOLECULE ELECTRICAL JUNCTIONS

Annual Review of Physical Chemistry, 2006
▪ Abstract  The objective of this review is to describe current experimental research of single-molecule electrical junctions in the context of various theoretical frameworks, with emphasis on the application of single-electron transistor theory to molecular junctions. Molecule quantum dots are at least an order of magnitude smaller than semiconductor
Yoram, Selzer, David L, Allara
openaire   +2 more sources

Voltage-Induced Single-Molecule Junction Planarization

Nano Letters, 2020
Probing structural changes of a molecule induced by charge transfer is important for understanding the physicochemical properties of molecules and developing new electronic devices. Here, we interrogate the structural changes of a single diketopyrrolopyrrole (DPP) molecule induced by charge transport at a high bias using scanning tunneling microscope ...
Yaping Zang   +9 more
openaire   +3 more sources

Single-molecule junctions beyond electronic transport

Nature Nanotechnology, 2013
The idea of using individual molecules as active electronic components provided the impetus to develop a variety of experimental platforms to probe their electronic transport properties. Among these, single-molecule junctions in a metal-molecule-metal motif have contributed significantly to our fundamental understanding of the principles required to ...
Sriharsha V, Aradhya   +1 more
openaire   +2 more sources

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