Results 171 to 180 of about 730,667 (367)

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Single Nucleotides Polymorphisms in COX2 Gene and their Association with Signs and Symptoms of Teething – A Pilot Study [PDF]

, 2023
Alana Gonçalvez Mauta, Caio Luiz Bitencourt Reis, Vinicius Broska Teodoro, Isabela Ribeiro Madalena, Christian Kirschneck, Peter Proff, Aleysson Olímpio Paza, Flares Baratto‐Filho, Daniela Silva Barroso de Oliveira, Érika Calvano Küchler, João Armando Brancher   +10 more
openalex   +1 more source

An alpine plant shows no decrease in genetic diversity associated with rapid post‐glacial range expansion

American Journal of Botany, EarlyView.
Abstract Premise: While range expansion is hypothesized to be a mechanism for species persistence under climate change, many eco‐evolutionary models describe demographic and genetic processes during expansion that may increase genetic drift, decrease genetic variation, and ultimately decrease relative fitness at the leading edge.
Mackenzie Urquhart‐Cronish, Colette S. Berg, Dylan Moxley, Olivia J. Rahn, Lila Fishman, Amy L. Angert   +5 more
wiley   +1 more source

Hot spots and single nucleotide polymorphisms on the interaction interface of RAD51 and p53 complex [PDF]

, 2018
Kleber Santiago Freitas e Silva
openalex   +1 more source

Single nucleotide polymorphism wars [PDF]

Nature Biotechnology, 1998
openaire   +2 more sources

Disentangling complex relationships and disjunctions in western Camassia: Integrating multiple criteria to resolve taxonomic boundaries

American Journal of Botany, EarlyView.
Abstract Premise Understanding genetic and morphological variability helps efforts to sustain landscapes and develop effective species concepts for resolving difficult groups. To unravel puzzling relationships and range disjunctions, we applied morphometrics, phenology, phylogenetics and population genetics in Camassia species with cultural, ecological,
Susan R. Kephart, Theresa M. Culley, Jenny K. Archibald, Robert Tunison, Kathryn E. Theiss, James E. Kephart   +5 more
wiley   +1 more source

Identification of deleterious single nucleotide polymorphism (SNP)s in the human TBX5 gene & prediction of their structural & functional consequences: An in silico approach

, 2021
A. M. U. B. Mahfuz, Md. Arif Khan, Promita Deb, Sharmin Jahan Ansary, Rownak Jahan   +4 more
openalex   +1 more source

GATA3 Deletion Associated With Juvenile Idiopathic Arthritis: Expanding the Phenotypic Spectrum of Hypoparathyroidism, Sensorineural Deafness, and Renal Dysplasia (HDR) Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss, Amanda V. Karam, Julia Shalen, David E. Tunkel, Belina Y. Yi, Kelsey S. Guthrie, Emily M. Kudalkar, Anna E. Patrick, Sonja A. Rasmussen   +8 more
wiley   +1 more source

Association Study of MAP3K1 SNPs and Risk Factors with Susceptibility to Esophageal Squamous Cell Carcinoma in a Chinese Population: A Case–Control Study

Pharmacogenomics and Personalized Medicine, 2020
Yiling Yang,1,* Qiang Zhou,2,* Huiwen Pan,2 Liming Wang,1,3 Cheng Qian4 1Department of Oncology, Affiliated People’s Hospital of Jiangsu University, Zhenjiang, Jiangsu 212002, People’s Republic of China; 2Department of Cardiothoracic Surgery,
Yang Y, Zhou Q, Pan H, Wang L, Qian C
doaj  

The Power of Proficiency Testing: Unraveling Single-Nucleotide Polymorphism Interference, With Potential Impact on Clinical Testing of Spinocerebellar Ataxia Type 3 [PDF]

, 2018
Cristiane M. Ida, Patrick A. Lundquist, Karen E. Weck, W. Edward Highsmith   +3 more
openalex   +1 more source