Results 211 to 220 of about 737,082 (371)

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Association of <i>PLA2G2A</i> single nucleotide polymorphism and cardiometabolic diseases in an HIV-infected population. [PDF]

Biomed Rep
Ndonwi EN, Nqebelele U, Matsha TE, Kengne AP.   +3 more
europepmc   +1 more source

Associations of Single Nucleotide Polymorphisms in the Adiponectin Gene with Adiponectin Levels and Cardio-Metabolic Risk Factors in Patients with Cancer

, 2011
Rasha Al Khaldi, Fahd Al‐Mulla, Shafika Al Awadhi, Kusum Kapila, Olusegun A. Mojiminiyi   +4 more
openalex   +1 more source

Genome‐Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis

Arthritis &Rheumatology, EarlyView.
Objective Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. Methods DNA methylation profiling was analyzed in 79
Gonzalo Borrego‐Yaniz, Ana Márquez, Elkyn Estupiñán‐Moreno, Laura C. Terrón‐Camero, Miguel A. González‐Gay, Santos Castañeda, Giuliana Guggino, David Saadoun, Pietro Lio, Simona Fontana, Martina Bonacini, Alessandro Rossi, Alberto Cavazza, Francesco Muratore, Carlo Salvarani, Nicolo Pipitone, Javier Martin, Stefania Croci, Lourdes Ortiz‐Fernández   +18 more
wiley   +1 more source

The Prognostic Value of the XPC rs2228001 Single Nucleotide Polymorphism in Cholangiocarcinoma. [PDF]

Liver Int
Wang G, Mantas A, Liu D, Al-Masri TM, Lueong SS, Siveke J, Luedde T, Ulmer TF, Amygdalos I, Vondran FWR, Lurje G, Neumann UP, Heij LR, Bednarsch J.   +13 more
europepmc   +1 more source

A centenarian single nucleotide polymorphism in collagen gene COL25A1 promotes longevity in C. elegans. [PDF]

NPJ Aging
Goyala A, Statzer C, Park JYC, Neundorf I, MacArthur MR, Gebauer JM, Ewald CY.   +6 more
europepmc   +2 more sources

Non-Invasive Prenatal Detection of Trisomy 13 Using a Single Nucleotide Polymorphism- and Informatics-Based Approach

, 2014
Megan P. Hall, Matthew D. Hill, Bernhard Zimmermann, Styrmir Sigurjonsson, Margaret Westemeyer, Jennifer Saucier, Zachary Demko, Matthew Rabinowitz   +7 more
openalex   +2 more sources

Transition From Psoriasis to Psoriatic Arthritis is Characterized by Distinct Alterations in Peripheral Blood Tc17, Th17, and CD4+ Effector Memory Cells

Arthritis &Rheumatology, EarlyView.
Objective Cellular mechanisms driving transition from psoriasis to psoriatic arthritis have remained largely elusive. Thus, we investigated changes within the peripheral blood T cell compartment associated with the transition phase. Methods In an observational study, 116 patients were examined and categorized into subgroups including psoriasis with at ...
Hanna Graßhoff, Sara Comdühr, Henry Nording, Jacob von Esebeck, Philine Letz, Miriam Prohaczka, Handan Gedik, Henner Zirpel, Elisabeth Spallek, Linh Ha‐Wissel, El‐Baraa Adjailia, Sabrina Arnold, Konstantinos Fourlakis, Sebastian Klapa, Ingo Eitel, Oliver J. Müller, Jens Y. Humrich, Gabriela Riemekasten, Diamant Thaçi, Peter Lamprecht   +19 more
wiley   +1 more source

Correction: Genetic diversity and population structure analyses of tropical maize inbred lines using Single Nucleotide Polymorphism markers. [PDF]

PLoS One
Gunundu R, Shimelis H, Tesfamariam SA.
europepmc   +1 more source

Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes

Arthritis &Rheumatology, Accepted Article.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. Variable copy number (CN) of C4 genes and retroviral HERV‐K element influence its function.
Javier Martínez‐López, Carlos Rangel‐Peláez, Inmaculada Rodriguez‐Martin, Alfredo Guillen‐Del‐Castillo, Carmen P Simeón‐Aznar, José L Callejas, International SSc Group; PRECISESADs Clinical Consortium, Oliver Distler, Susanna M Proudman, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), Nicolas Hunzelmann, Gianluca Moroncini, Jeska K de Vries‐Bouwstra, Ariane L Herrick, Yannick Allanore, Marta E. Alarcon‐Riquelme, Lorenzo Beretta, Shervin Assassi, Christopher P Denton, Maureen D Mayes, Javier Martin, Marialbert Acosta‐Herrera, Martin Kerick   +23 more
wiley   +1 more source