Results 331 to 340 of about 730,667 (367)

Hypertension and single nucleotide polymorphisms

Current Hypertension Reports, 2000
Hypertension is a common, complex disease phenotype that has been intensively studied to identify susceptibility loci in humans. Candidate genes continue to be uncovered via genetic analysis in model organisms through linkage analysis with families and/or sib-pairs and through association studies using sequence variants in genes that play a role in key
M J, Rieder, D A, Nickerson
openaire   +2 more sources

Single-Nucleotide Polymorphism Mapping

2006
Single-nucleotide polymorphism (SNP) mapping is the easiest and most reliable way to map genes in Caenorhabditis elegans. SNPs are extremely dense and usually have no associated phenotype, making them ideal markers for mapping. SNP mapping has three steps.
M Wayne, Davis, Marc, Hammarlund
openaire   +2 more sources

Classifying single nucleotide polymorphisms in humans

Molecular Genetics and Genomics, 2021
Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation amongst the human population and are key to personalized medicine. New tests are presented to distinguish pathogenic/malign (i.e., likely to contribute to or cause a disease) from nonpathogenic/benign SNPs, regardless of whether they occur in coding (exon) or noncoding
Shima Azizzadeh-Roodpish, Max H Garzon, Sambriddhi Mainali   +2 more
openaire   +2 more sources

Inherently electroactive graphene oxide nanoplatelets as labels for single nucleotide polymorphism detection.

ACS Nano, 2012
Graphene materials are being widely used in electrochemistry due to their versatility and excellent properties as platforms for biosensing. However, no records show the use of inherent redox properties of graphene oxide as a label for detection. Here for
A. Bonanni, Chun Kiang Chua, Guanjia Zhao, Zdenek Sofer, M. Pumera   +4 more
semanticscholar   +1 more source

Cytokine Single Nucleotide Polymorphisms in Iran

Journal of Interferon & Cytokine Research, 2006
Overall expression and secretion of cytokines are dependent on genetic nucleotide variations within or adjacent to regulatory regions of cytokine genes. This study allows the comparison of the prevalence of particular genetic markers. In 40 Iranian healthy subjects, cytokine single nucleotide polymorphisms (SNPs) were used to determine allelic and ...
Mortaza, Bagheri, Davood, Omrani, Isa, Abdi-Rad   +2 more
openaire   +2 more sources

Single-Nucleotide Polymorphism Analysis by Pyrosequencing

Analytical Biochemistry, 2000
There is a growing demand for high-throughput methods for analysis of single-nucleotide polymorphic (SNP) positions. Here, we have evaluated a novel sequencing approach, pyrosequencing, for such purposes. Pyrosequencing is a sequencing-by-synthesis method in which a cascade of enzymatic reactions yields detectable light, which is proportional to ...
A, Ahmadian, B, Gharizadeh, A C, Gustafsson, F, Sterky, P, Nyrén, M, Uhlén, J, Lundeberg   +6 more
openaire   +2 more sources

The single nucleotide polymorphism story

Pharmacogenetics, 2003
Sandrine, Barbaux, François, Cambien
openaire   +2 more sources

A single-nucleotide polymorphism causes smaller grain size and loss of seed shattering during African rice domestication

Nature Plants, 2017
Wenguang Wu, Xiaoyun Liu, Muhua Wang, Rachel S. Meyer, Xiaojin Luo, M. Ndjiondjop, Lubin Tan, Jianwei Zhang, Jianzhon Wu, H. Cai, Chuanqing Sun, Xiangkun Wang, R. Wing, Zuofeng Zhu   +13 more
semanticscholar   +1 more source

single nucleotide polymorphism

2009
(SNP, pronounced “snips”) variation at just a single base of a four-bases (syn. nucleotides) long codon; it is assumed that SNPs predispose individuals to develop certain diseases but also to respond or not to certain drugs; → see also genom, pharmacogenetics.
openaire   +1 more source

Single-Nucleotide Polymorphisms

2013
Børsting, Claus, Morling, Niels
  +5 more sources