Results 51 to 60 of about 709,137 (285)

Construction and analysis of single nucleotide polymorphism–single nucleotide polymorphism interaction networks

IET Systems Biology, 2013
The study of gene regulatory network and protein–protein interaction network is believed to be fundamental to the understanding of molecular processes and functions in systems biology. In this study, the authors are interested in single nucleotide polymorphism (SNP) level and construct SNP–SNP interaction network to understand genetic characters and ...
Michael K. Ng, Xutao Li, Zhi-Ping Liu, Luonan Chen, Yang Liu   +4 more
openaire   +4 more sources

Next generation sequencing reveals the antibiotic resistant variants in the genome of Pseudomonas aeruginosa [PDF]

, 2017
Rapid progress in next generation sequencing and allied computational tools have aided in identification of single nucleotide variants in genomes of several organisms. In the present study, we have investigated single nucleotide polymorphism (SNP) in ten
Ramanathan, Babu *
core   +1 more source

Single nucleotide polymorphisms and periodontitis

Dentistry and Medical Research, 2014
The susceptibility to various diseases is studied with association to genetic polymorphisms. Among these polymorphisms, single-nucleotide polymorphisms (SNPs) are very common throughout the genome. The recent advances in genetic assay techniques and increase in SNP databases are paving a way for investigation of susceptibility genes for periodontitis ...
Khaled Awidat, Syed Wali Peeran, Marei Hamad Al Mugrabi, Ramalingam Karthikeyan, Omar Basheer, Manohar Murugan   +5 more
openaire   +3 more sources

Functional single nucleotide polymorphism-based association studies

Human Genomics, 2006
Association studies hold great promise for the elucidation of the genetic basis of diseases. Studies based on functional single nucleotide polymorphisms (SNPs) or on linkage disequilibrium (LD) represent two main types of designs.
Carlton Victoria EH, Ireland James S, Useche Francisco, Faham Malek   +3 more
doaj   +1 more source

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.

American Journal of Human Genetics, 2004
Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting approximately 1% of the adult population worldwide, with an estimated heritability of 60%.
A. Begovich, V. Carlton, L. Honigberg, S. Schrodi, A. Chokkalingam, H. Alexander, K. Ardlie, Qiqing Huang, Ashley M. Smith, J. Spoerke, Marion T. Conn, Monica Chang, Sheng-Yung P. Chang, R. Saiki, J. Catanese, Diane U. Leong, Veronica E. Garcia, L. McAllister, D. Jeffery, Annette Lee, F. Batliwalla, E. Remmers, L. Criswell, M. Seldin, D. Kastner, C. Amos, J. Sninsky, P. Gregersen   +27 more
semanticscholar   +1 more source

Novel single nucleotide polymorphism-based assay for genotyping Mycobacterium avium subsp. paratuberculosis [PDF]

, 2016
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power.
Bryant, Josephine, Goldstone, Robert J., Inácio, João, Leão, Célia, McLuckie, Joyce, Smith, David G.E., Stevenson, Karen   +6 more
core   +2 more sources

Development of a Single Nucleotide Polymorphism Barcode to Genotype Plasmodium vivax Infections

PLoS Neglected Tropical Diseases, 2015
Plasmodium vivax, one of the five species of Plasmodium parasites that cause human malaria, is responsible for 25–40% of malaria cases worldwide. Malaria global elimination efforts will benefit from accurate and effective genotyping tools that will ...
M. Baniecki, Aubrey Faust, S. Schaffner, Daniel J. Park, K. Galinsky, R. Daniels, Elizabeth J. Hamilton, M. U. Ferreira, N. Karunaweera, D. Serre, P. Zimmerman, Juliana M. Sá, T. Wellems, L. Musset, E. Legrand, Alexandre Melnikov, D. Neafsey, S. Volkman, D. Wirth, Pardis C Sabeti   +19 more
semanticscholar   +1 more source

Genetic variants associated with the root system architecture of oilseed rape (Brassica napus L.) under contrasting phosphate supply [PDF]

, 2017
Breeding crops with ideal root system architecture for efficient absorption of phosphorus is an important strategy to reduce the use of phosphate fertilizers.
Broadley, Martin R., Cai, Hongmei, Chen, Yanling, Ding, Guangda, Grandke, Fabian, Jin, Kemo, Shi, Dexu, Shi, Lei, Thomas, Catherine L., Wang, Xiaohua, Xu, Fangsen, Xu, Ping, Yi, Bin   +12 more
core   +1 more source

Cryptic Variation in the Human Mutation Rate [PDF]

, 2009
The mutation rate is known to vary between adjacent sites within the human genome as a consequence of context, the most well-studied example being the influence of CpG dinucelotides.
Eyre-Walker, Adam, Hodgkinson, Alan, Ladoukakis, Emmanuel   +2 more
core   +3 more sources

Single nucleotide polymorphism (SNP) discovery in polyploid plants

浙江大学学报. 农业与生命科学版, 2011
Single nucleotide polymorphism (SNP) is a kind of DNA polymorphism in genome which results from the variance of single nucleotide. In diploid organisms (such as human, Arabidopsis thaliana, Oryza sativa, etc.), many SNP markers were discovered as genetic
HE Dao-hua, XING Hong-yi, ZHAO Jun-xing, ZHAO Yan-ning, QI Cheng, WANG Yan-ting   +5 more
doaj   +1 more source