Results 51 to 60 of about 9,699,132 (284)

SPECIFICITY OF CHILDREN'S SOCIALIZATION IN COMPLETE AND PARENT FAMILIES

open access: yesСоціально-економічні відносини в цифровому суспільстві
The article describes the specifics of the socialization process of children in complete and incomplete families. The research is based on the use of various methods: parental surveys and psychological tests.
Mariia Blikhar, Iryna Subashkevych
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Single-parent families and in-work poverty [PDF]

open access: yes, 2018
Single-parent families face unique challenges when it comes to in-work poverty. Without a second caregiver and earner, single parents have to compete with dual-earner couples for their position in ...
Nieuwenhuis, Rense, Maldonado, Laurie C.
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Redéfinir la famille pour en faire partie. Les mobilisations des "Femmes Chefs de famille" (France, 1963-1982)

open access: yesGenre & Histoire, 2016
In 1963, activists of a French pro-family union created the first Committees for women heads of household, which gathered together widows, divorcees and single mothers.
Fiona Friedli
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Parent family

open access: yes, 1976
Interview with members of the Parent/Leveque family, including Della Parent (nee Leveque, 1903-1998) of Nakusp and son Len Parent (1927-2017) of Delta, formerly of Nakusp, conducted by Milton Parent ...

core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Parent & Leveque family

open access: yes, 1970
Interview with members of the Parent/Leveque family, including Della Parent (nee Leveque, 1903-1998) of Nakusp and Joseph Parent (1898-1972), first mayor of Nakusp, conducted by Milton Parent at Milton Parent's' home in Burnaby, British Columbia, October

core  

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

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