Results 61 to 70 of about 1,136 (207)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Bibliotherapy Uses Kinemaster in Increasing Teenage Happiness from Single Parent Family

Bisma The Journal of Counseling
Divorce in Indonesia is currently increasing from year to year. Parental separation causes unhappiness in adolescents. Various pressures felt by adolescents have not been effective with conventional bibliotherapy to overcome it.
Neni Elvira Z., Firman
doaj   +1 more source

Single Parent Families in Kalmykia (a case study based on statistical data)

Oriental Studies, 2018
The article deals with a type of families - the single parent family - the number of which has been increasing dramatically in recent decades. Statistical data signify that there is regional disparity in terms of the proportion of single parent families ...
B. B. Nuskhaeva
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Die bediening aan enkelouergesinne met adolessente: ’n inklusiewe en intergenerasionele uitdaging

In die Skriflig
Serving single-parent families with adolescents: An inclusive and intergenerational challenge. This article focused on the ministry to single-parent families after divorce.
Johan W. Scholtz, Malan Nel, Jacques Beukes   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

PREVALENCE AND CORRELATES OF ADJUSTMENT DISORDER IN SINGLE PARENT MOTHERS

Pakistan Armed Forces Medical Journal, 2020
Objective: To investigate prevalence and difference of adjustment disorder in single parent mothers. Study Design: Cross-sectional analytical study. Place and Duration of Study: Department of Psychology, University of Gujrat, from Jan to Apr 2019.
Iram Naz, Khushnood Fatima, Razia Anjum
doaj  

Mental health among single mothers in Cyprus: a cross-sectional descriptive correlational study

BMC Women's Health, 2019
Background International literature reveals that single mothers experience increased levels of chronic stress, which is mainly due to economic hardship and reduced levels of social support. Eventually this leads to psychological distress.
Elena Rousou, Christiana Kouta, Nicos Middleton, Maria Karanikola   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Different Family Arrangements from the Perspective of Pre-teens [PDF]

Psicologia: Teoria e Pesquisa
Economic and social transformations, in the second half of the 20th century, led to changes in concepts of family. This study aimed to investigate the conceptual perspective of 40 children regarding the new configurations of the contemporary family.
Lyege de Lima Borges Bastos, Maria Auxiliadora Dessen   +1 more
doaj   +1 more source