Results 81 to 90 of about 88,367,282 (284)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Single line to ground Fault Detection Using More Criterions in Distribution System Based on Voltage Variation

open access: yes工程科学与技术, 2014
:Based on the voltage variations,a new approach called ‘lower threshold value,more criterions’ was proposed to enhance the single-line-to-ground fault detection sensitivity in neutral un-effective gounded system.
张文海, 肖先勇, 范康林
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Modelling and Simulation of Mho Type Distance Relay for High Voltage Transmission Line Protection Using MATLAB Software

open access: yesJAREE (Journal on Advanced Research in Electrical Engineering), 2019
Transmission lines are an important part of a power system. Transmission lines have high power transmission capacity and they are prone to faults of larger magnitudes. Various faults occur in transmission lines. Therefore, protection relays are necessary
win win tun, Ohn Zin Lin, Han Su Yin
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A Novel Logic To Stator Single Phase - To - Ground Fault For Power-Former

open access: yes, 2017
The stator single-phase to ground fault is one of the most common fault that a Generator will suffer. If such fault is neglected then there are chances of converting it into phase to phase fault. So there is need to detect and isolate the faulty part from the rest of the system as early as possible.
SHAKIL D. JAMADAR   +2 more
openaire   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

Single Line-to-Ground Fault Type Multilevel Classification in Distribution Network Using Realistic Recorded Waveform

open access: yes, 2023
The further identification of fault types for single line-to-ground faults (SLGFs) in distribution networks is conducive to determining the cause of grounding faults and formulating targeted measures for hidden danger treatment and fault prevention.
Yue Liu   +4 more
core   +1 more source

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