Multiple flow profiles for two-phase flow in single microfluidic channels through site-selective channel coating [PDF]
Hella Logtenberg+4 more
openalex +1 more source
Single phase flow pressure drop and heat transfer in rectangular metallic microchannels
A. M. Sahar+5 more
semanticscholar +1 more source
Scaling up microdroplet production with post-array devices. [PDF]
Masui S, Kanno Y, Nisisako T.
europepmc +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
Explicit filtering to obtain grid-spacing-independent and discretization-order-independent large-eddy simulation of compressible single-phase flow [PDF]
Senthilkumaran Radhakrishnan+1 more
openalex +1 more source
Single and Two-Phase Flows on Chemical and Biomedical Engineering [PDF]
Ricardo Dias+72 more
openalex +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
Single-shot reconstruction of three-dimensional morphology of biological cells in digital holographic microscopy using a physics-driven neural network. [PDF]
Kim J, Kim Y, Lee HS, Seo E, Lee SJ.
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte+10 more
wiley +1 more source