Results 71 to 80 of about 760,907 (355)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Novel Single-Stage Electrolytic Capacitor-Less Buck-Boost Inverter

Energies
Nowadays, single-phase, single-stage, buck-boost power inverters are mostly considered to be used for renewable energy source applications due to their wide range of capabilities.
Youn-Ok Choi, Khai M. Nguyen
doaj   +1 more source

RANCANG BANGUN INVERTER JEMBATAN PENUH FASA TUNGGAL DENGAN TAPIS LC [PDF]

, 2016
Dalam lima tahun belakangan ini, inverter fasa tunggal telah digunakan dalam banyak jenis aplikasi seperti UPS, konversi energi terbarukan, dan catu daya.
Wijaya, Fajar Witama
core  

An Improved SPWM-Based Control with Over-Modulation Strategy of the Third Harmonic Elimination for a Single-Phase Inverter

, 2018
In single-phase inverter systems (grid-connected, Uninterrupted Power Supply systems or motor drives), the high quality Total Harmonic Distortion (THD) factor must always be considered, along with the utilization rate of the DC link.
A. Hren, F. Mihalič
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

An efficient power decoupling topology circuit based on a novel three-port three-switches flyback series circuit.

PLoS ONE
Both filter inductors, electrolytic capacitors, and radiators play a significant role in the inverter of a PV (Photovoltaic) power generation system. These three parts are the largest in an inverter, which affects the performance of the inverter.
Wang Jinpeng, Kang Yufang, Yao Qingxue, Jeremy Gillbanks, Zhao Xin   +4 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Single Phase Fault Tolerance Multilevel Inverter

IOP Conference Series: Earth and Environmental Science
Abstract In high-and medium-voltage systems, multilevel inverters (MLIs) have lately attracted a lot of interest utilized in a number of industrial uses. Low harmonic, high-power output at medium voltages, modularity—high. Among the various advantages of MLIs are several content ones. MLI dependability is really crucial. Various types of
Ragaleela Dalapati Rao, K. Prathyusha, L Tulasi Lakshmi, M. Rithwak, Sampath Babu Polanki, Vishnu Chaitanya Sidhardha Karimella   +5 more
openaire   +1 more source

Design of Quadratic Optimal Regulator System for State Space Model of Single Phase Inverter Both in Standalone and Gridtie Modes [PDF]

, 2014
Since in 3-phase systems, the reliability of 3-phase Inverter is not good, under such situations Paralleled Inverter Systems are used. Parallel Inverter operation has a major role in uninterruptible power system (UPS) applications. Most of the standalone
Kiran, N. (Nagulapati), Kumar, V. A. (V), Rao, D. A. (Dhanamjaya)   +2 more
core  

A three-level common-mode voltage eliminated inverter with single dc supply using flying capacitor inverter and cascaded H-bridge [PDF]

, 2014
A three-level common-mode voltage eliminated in- verter with single dc supply using flying capacitor inverter and cascaded H-bridge has been proposed in this paper.
García Franquelo, Leopoldo, Gopakumar, K., Kumar, P. Roshan, León Galván, José Ignacio, Mathew, K., Rajeevan, P. P.   +5 more
core   +1 more source