Results 91 to 100 of about 18,902 (308)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Practical application of on-line partial discharge monitoring technique on 500kV shunt reactor [PDF]

open access: yes, 2003
Considering the damage mechanism of oil-impregnated paper insulation in power transformers, shunt reactors and other high voltage electrical apparatus caused by partial discharge, a concept of “destructive partial discharge” is introduced in this paper ...
Fu, M, Wang, S, Chen, G
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Test results of resonant single wire system transmitting power to the infrastructure objects of the JSC “RZD”

open access: yesВестник Научно-исследовательского института железнодорожного транспорта, 2018
The paper provides test results of pilot sample of resonant single wire transmission system to a distance of 2000 m at a higher frequency. Cable power lines used as the power line based on coaxial cable.
D. V. Ermolenko   +2 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Investigation оf Microprocessor Differential Protection оf Power Reducing Transformer

open access: yesНаука и техника, 2014
The paper presents investigations on functioning of a differential protection of 110 kV reducing transformer  with internal faults using computer simulation.
F. A. Romaniuk, M. S. Loman
doaj  

Low-Frequency Transient Model of Single-Phase Four-Limb Converter Transformer Considering the Nonlinear Excitation Characteristics of the Iron Core

open access: yesApplied Sciences
Transformer modeling is a crucial method for analyzing transient phenomena such as inrush currents. The primary characteristic of a transformer transient model is its ability to reflect how the transformer’s structure and material properties influence ...
Xichen Pei   +6 more
doaj   +1 more source

Low voltage single-phase excitation for power transformers [PDF]

open access: yes, 2014
To verify that the inner design and its performance are satisfactory and that there are no failures in the winding insulation system and core displacement during long-trip transport, we need to do several tests such as SFRA test or single-phase ...
Zhan Yangang, Yangang, Zhan
core   +1 more source

Impulse transfer and voltage gain in single phase low power transformers [PDF]

open access: yes, 2012
RESUMEN: Se evaluó la transferencia de impulsos de tensión 1.2/50μs y 3/23μs del primario al secundario, en tres transformadores monofásicos utilizados en aplicaciones electrónicas, uno de 18W, otro de 85W y un autotransformador de 50W, considerándolos ...
Valencia Velásquez, Jaime Alejandro   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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