Results 91 to 100 of about 11,397,847 (296)

Single- and Dual-Stage High-Purity Oxygen Production Using Silver-Exchanged Titanosilicates (Ag-ETS-10)

open access: yes, 2018
High-purity (>99.5%) O2 production from air with silver-exchanged titanosilicates (Ag-ETS-10) using multiple single- and dual-stage vacuum swing adsorption (VSA) cycle configurations was investigated through process simulation, and optimization.
Arvind Rajendran (1749316)   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Performance Investigation on SITP’s 60 K High Frequency Single-Stage Coaxial Pulse Tube Cryocoolers.

open access: yes, 2008
Presented at the 16th International Cryocooler Conference, held May 17-20, 2008 in Atlanta, Georgia.A series of 60 K high frequency single-stage coaxial pulse tube cryocoolers has been developed to provide reliable low-noise cooling at 60 K for space ...
Yang, K. X.   +5 more
core  

CFD analysis to understand the flow behaviour of a single stage transonic Axial flow compressor [PDF]

open access: yes, 2013
This paper comprises the Computational Fluid Dynamic (CFD) analysis to investigate the flow behaviour of a high speed single stage transonic axial flow compressor.
Shobhavathy, MT, Premakara , Hanoca
core  

Single-cell RNA-seq expression of late stage asexual parasites identifies three distinct populations.

open access: yes, 2019
A) Principal component analysis (PCA) was used to visualize the clustering of 46 single late stage asexual transcriptomes. B) Consensus clustering indicates that parasites within the same cluster show the strongest similarity when compared to parasites ...
Hélène Fradin (228950)   +4 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Single-stage multidisciplinary surgical repair of a secondary aortoesophageal fistula: A technical case report with 3-year uneventful follow-upCentral MessagePerspective

open access: yesJTCVS Techniques
Objective: Secondary aortoesophageal fistula (AEF) after thoracic endovascular aortic repair (TEVAR) is a rare but life-threatening complication. Definitive treatment guidelines are lacking, and surgical management has traditionally relied on staged ...
Adam Zeyara, MD   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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