Results 101 to 110 of about 7,610,196 (308)
A Modified Single-Phase Single-Stage Boost Inverter [PDF]
This paper presents a modified single stage single phase inverter with four switches. The proposed inverter has important features such as continuous input current, voltage buck and boost with single stage conversion, short circuit safety and operation ...
Hadi Khoramdel +3 more
doaj +1 more source
Single-stage percutaneous extraction of renal calculi
The routine application of percutaneous techniques to the management of patients with renal calculous disease is evolving rapidly. Of 74 patients requiring surgery for renal calculous disease, 64 (86%) were deemed suitable candidates for percutaneous stone removal rather than standard open surgical intervention.
S B, Streem +3 more
openaire +2 more sources
High-purity (>99.5%) O2 production from air with silver-exchanged titanosilicates (Ag-ETS-10) using multiple single- and dual-stage vacuum swing adsorption (VSA) cycle configurations was investigated through process simulation, and optimization.
Arvind Rajendran (1749316) +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
TWO-STAGE QUANTILE REGRESSION WHEN THE FIRST STAGE IS BASED ON QUANTILE REGRESSION [PDF]
We present the asymptotic properties of double-stage quantile regression estimators with random regressors, where the first stage is based on quantile regressions with the same quantile as in the second stage, which ensures robustness of the estimation ...
Tae-Hwan Kim, Christophe Muller
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
STAGE - Data Management Plan n°1
The Data Management Plan (DMP) explains the management decisions made to ensure these aspects, as well as the preservation of the research products once the project ends.
Fras, Jeanne, Bardiot, Clarisse
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source

