Results 101 to 110 of about 7,610,196 (308)

A Modified Single-Phase Single-Stage Boost Inverter [PDF]

open access: yesمجله مدل سازی در مهندسی
This paper presents a modified single stage single phase inverter with four switches. The proposed inverter has important features such as continuous input current, voltage buck and boost with single stage conversion, short circuit safety and operation ...
Hadi Khoramdel   +3 more
doaj   +1 more source

Single-stage percutaneous extraction of renal calculi

open access: yesCleveland Clinic Journal of Medicine, 1985
The routine application of percutaneous techniques to the management of patients with renal calculous disease is evolving rapidly. Of 74 patients requiring surgery for renal calculous disease, 64 (86%) were deemed suitable candidates for percutaneous stone removal rather than standard open surgical intervention.
S B, Streem   +3 more
openaire   +2 more sources

Single- and Dual-Stage High-Purity Oxygen Production Using Silver-Exchanged Titanosilicates (Ag-ETS-10)

open access: yes, 2018
High-purity (>99.5%) O2 production from air with silver-exchanged titanosilicates (Ag-ETS-10) using multiple single- and dual-stage vacuum swing adsorption (VSA) cycle configurations was investigated through process simulation, and optimization.
Arvind Rajendran (1749316)   +4 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

TWO-STAGE QUANTILE REGRESSION WHEN THE FIRST STAGE IS BASED ON QUANTILE REGRESSION [PDF]

open access: yes
We present the asymptotic properties of double-stage quantile regression estimators with random regressors, where the first stage is based on quantile regressions with the same quantile as in the second stage, which ensures robustness of the estimation ...
Tae-Hwan Kim, Christophe Muller
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

STAGE - Data Management Plan n°1

open access: yes
The Data Management Plan (DMP) explains the management decisions made to ensure these aspects, as well as the preservation of the research products once the project ends.
Fras, Jeanne, Bardiot, Clarisse
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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