We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Single-Stage vs. Multi-Stage Reconstruction in Multi-Ligament Knee Injuries: A Systematic Review and Meta-Analysis of Outcomes and Complications. [PDF]
Jaibaji M +6 more
europepmc +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
A prospective longitudinal study on the outcome of augmented conscious sedation in single-stage adjustable strabismus surgery. [PDF]
Anandhi IM +5 more
europepmc +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Debridement Technique for Single-Stage Revision Shoulder Arthroplasty. [PDF]
Kolakowski L +6 more
europepmc +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
A smart single stage solar battery driven desalination system with hybrid MPPT and optimal control for brackish water treatment. [PDF]
Bettahar F +5 more
europepmc +1 more source
Single-stage delayed hybrid reconstruction after failed implant-based breast surgery using the pedicled thoracodorsal artery perforator flap: a report of three cases. [PDF]
Shah R +3 more
europepmc +1 more source
Successful Prevention of Bronchopleural Fistula in Single-Stage Esophagectomy and Right Lower Lobectomy: A Case Report. [PDF]
Oki T, Iizuka S, Tomatsu M, Nakamura T.
europepmc +1 more source

