Results 121 to 130 of about 13,531,309 (317)

Cnidarian Cell Type Diversity and Regulation Revealed by Whole-Organism Single-Cell RNA-Seq

, 2018
International audienceThe emergence and diversification of cell types is a leading factor in animal evolution. So far, systematic characterization of the gene regulatory programs associated with cell type specificity was limited to few cell types and few
Loe-Mie, Yann, Heather Marlow, Amos Tanay, Patrick R.H. Steinmetz, Marlow, Heather, Mailhé, Marie-Pierre, Zohar Mukamel, Sandrine Schmutz, Steinmetz, Patrick, Arnau Sebé-Pedrós, Baptiste Saudemont, Spitz, François, Novault, Sophie, Mukamel, Zohar, Marie-Pierre Mailhé, Lifshitz, Aviezer, Yann Loe-Mie, Plessier, Flora, Aviezer Lifshitz, Schmutz, Sandrine, Renno, Justine, François Spitz, Elad Chomsky, Saudemont, Baptiste, Chomsky, Elad, Justine Renno, Sebé-Pedrós, Arnau, Flora Plessier, Sophie Novault, Tanay, Amos   +29 more
core   +1 more source

Facts, Challenges, Difficulties and Hopes in Single-Cell Biology: Physiopathological Studies [PDF]

, 2015
Single-cell approaches are being increasingly used to unravel the many diverse mechanisms underlying biological processes that characterize each cell irrespective of the influx of other cells even within the same tissue. Consequently, the interference of
Francesco Salvatore1, 2*, TOMAIUOLO, ROSSELLA, CARIATI, FEDERICA   +2 more
core   +1 more source

Single-cell specificity analysis.

, 2022
A. The Jaccard-Index is used to compare the imputed profiles from SIMPA with the origin human bulk profile used to create a simulated sparse profile and the consensus profile representing the remaining experiments available for the same biosample-target ...
Miguel A. Andrade-Navarro (31443), Jean Fred Fontaine (12988237), Steffen Albrecht (483443), Tommaso Andreani (7880516)   +3 more
core   +1 more source

scGSECA:identification of altered biological processes in single-cell RNA-sequencing data by discretization of expression profiles

, 2023
Bimodality of the distribution of expression levels has been observed in bulk RNA-seq. Two possible explanations underpin this kind of partitioning and refer to opposite paradigmatic models.
Salvatore Oliviero, Michele Caselle, Matteo Cereda, Andrea Lauria, Serena Peirone, Francesca Priante, Sarah Perrone   +6 more
core   +1 more source

Potato: from functional genomics to genetic improvement

Molecular Horticulture
Potato is the most widely grown non-grain crop and ranks as the third most significant global food crop following rice and wheat. Despite its long history of cultivation over vast areas, slow breeding progress and environmental stress have led to a ...
Li Qu, Xueqing Huang, Xin Su, Guoqing Zhu, Lingli Zheng, Jing Lin, Jiawen Wang, Hongwei Xue   +7 more
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Single-cell annotation and diagnostic relevance scheme.

, 2023
Single-cell annotation and diagnostic relevance scheme.
Torsten Haferlach (65226), Christian Matek (2040223), Matthias Hehr (14797745), Christian Pohlkamp (14797748), Carsten Marr (173699), Peter Lienemann (2072767), Ario Sadafi (10215521), Karsten Spiekermann (532234)   +7 more
core   +1 more source

PRMT7 deficiency causes dysregulation of the HCN channels in the CA1 pyramidal cells and impairment of social behaviors

Experimental and Molecular Medicine, 2020
Neuroscience: Finding the brakes in the autistic brain Disrupted expression of an ion channel that helps stabilize brain cell activity contributes to behavioral symptoms in mice resembling those seen in autism spectrum disorders (ASDs). Nerve cell firing
Seul-Yi Lee, Tuan Anh Vuong, Hyun-Kyung So, Hyun-Ji Kim, Yoo Bin Kim, Jong-Sun Kang, Ilmin Kwon, Hana Cho   +7 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source