Results 21 to 30 of about 3,543,075 (195)
Single Cell Genomics meeting in Stockholm: from single cells to cell types [PDF]
Genome Biology, 2014 AbstractA report on the second Single Cell Genomics conference held in Stockholm, Sweden, September 9-11, 2014.
Scialdone, Antonio +2 more
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Identification of cell types from single cell data using stable clustering
Scientific Reports, 2020 Single-cell RNA-seq (scRNASeq) has become a powerful technique for measuring the transcriptome of individual cells. Unlike the bulk measurements that average the gene expressions over the individual cells, gene measurements at individual cells can be ...
Azam Peyvandipour +3 more
doaj +1 more source
Experimental & Molecular Medicine, 2022 AbstractSingle-cell ribonucleic acid (RNA) sequencing (scRNA-seq) is an effective technique for estimating the cellular composition and transcriptional profiles of individual cells from fresh tissue. Single-nucleus RNA sequencing (snRNA-seq) is necessary to perform this type of analysis in frozen or difficult-to-dissociate tissues, which cannot be ...
Jin-Mi Oh +6 more
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Single-cell RNA sequencing identifies distinct mouse medial ganglionic eminence cell types. [PDF]
, 2017 Many subtypes of cortical interneurons (CINs) are found in adult mouse cortices, but the mechanism generating their diversity remains elusive. We performed single-cell RNA sequencing on the mouse embryonic medial ganglionic eminence (MGE), the major ...
Chen, Ying-Jiun J +7 more
core +1 more source
Plant single-cell and single-cell-type metabolomics
Trends in Plant Science, 2014 In conjunction with genomics, transcriptomics, and proteomics, plant metabolomics is providing large data sets that are paving the way towards a comprehensive and holistic understanding of plant growth, development, defense, and productivity. However, dilution effects from organ- and tissue-based sampling of metabolomes have limited our understanding ...
Biswapriya B, Misra +2 more
openaire +3 more sources
RNA splicing programs define tissue compartments and cell types at single-cell resolution
eLife, 2021 The extent splicing is regulated at single-cell resolution has remained controversial due to both available data and methods to interpret it. We apply the SpliZ, a new statistical approach, to detect cell-type-specific splicing in >110K cells from 12 ...
Julia Eve Olivieri +11 more
doaj +1 more source
Combined aptamer and transcriptome sequencing of single cells. [PDF]
, 2018 The transcriptome and proteome encode distinct information that is important for characterizing heterogeneous biological systems. We demonstrate a method to simultaneously characterize the transcriptomes and proteomes of single cells at high throughput ...
Abate, Adam R +3 more
core +2 more sources
Nature Communications, 2021 The contribution of distinct types of dorsal root ganglion neurons to chronic pain is unclear. Here, the authors molecularly profile non-human primate sensory neurons and show that genome-wide associations converge on two neuronal types with different ...
Jussi Kupari +14 more
doaj +1 more source
Single-cell analysis of bovine muscle-derived cell types for cultured meat production
Frontiers in Nutrition, 2023 Cultured meat technologies leverage the proliferation and differentiation of animal-derived stem cells ex vivo to produce edible tissues for human consumption in a sustainable fashion.
Tobias Messmer +12 more
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Cornea organoids from human induced pluripotent stem cells. [PDF]
, 2017 The cornea is the transparent outermost surface of the eye, consisting of a stratified epithelium, a collagenous stroma and an innermost single-cell layered endothelium and providing 2/3 of the refractive power of the eye. Multiple diseases of the cornea
Adams, Sheila M +5 more
core +3 more sources