Results 61 to 70 of about 3,543,075 (195)
Single cell electroporation on chip [PDF]
, 2006 In this thesis the results of the development of microfluidic cell trap devices for single cell electroporation are described, which are to be used for gene transfection.
Valero, Ana
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Evaluation of Dynamic Cell Processes and Behavior Using Video Bioinformatics Tools [PDF]
, 2015 Just as body language can reveal a person’s state of well-being, dynamic changes in cell behavior and morphology can be used to monitor processes in cultured cells.
A Valavanidis +35 more
core +1 more source
HArmonized single-cell RNA-seq Cell type Assisted Deconvolution (HASCAD)
BMC Medical Genomics, 2023 Abstract Background Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using reference gene expression signatures of distinct cell types.
Yen-Jung Chiu +2 more
openaire +3 more sources
gCAnno: a graph-based single cell type annotation method [PDF]
BMC Genomics, 2020 Abstract Background Current single cell analysis methods annotate cell types at cluster-level rather than ideally at single cell level. Multiple exchangeable clustering methods and many tunable parameters have a substantial impact on the clustering outcome, often leading to incorrect cluster ...
Yang, Xiaofei +5 more
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The importance of detailed epigenomic profiling of different cell types within organs. [PDF]
, 2016 The human body consists of hundreds of kinds of cells specified from a single genome overlaid with cell type-specific epigenetic information. Comprehensively profiling the body's distinct epigenetic landscapes will allow researchers to verify cell types ...
Borok, Zea +4 more
core +1 more source
Target shape dependence in a simple model of receptor-mediated endocytosis and phagocytosis [PDF]
, 2016 Phagocytosis and receptor-mediated endocytosis are vitally important particle uptake mechanisms in many cell types, ranging from single-cell organisms to immune cells.
Endres, Robert G., Richards, David M.
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MAGNETO: Cell type marker panel generator from single-cell transcriptomic data
Journal of Biomedical Informatics, 2023 Single-cell RNA sequencing experiments produce data useful to identify different cell types, including uncharacterized and rare ones. This enables us to study the specific functional roles of these cells in different microenvironments and contexts.
Tangherloni, Andrea +4 more
openaire +2 more sources
BMC Bioinformatics, 2020 Background In recent years, the rapid development of single-cell RNA-sequencing (scRNA-seq) techniques enables the quantitative characterization of cell types at a single-cell resolution.
Xiaoyang Chen, Shengquan Chen, Rui Jiang
doaj +1 more source
Identification of Cell Types from Single-Cell Transcriptomic Data
, 2019 Unprecedented technological advances in single-cell RNA-sequencing (scRNA-seq) technology have now made it possible to profile genome-wide expression in single cells at low cost and high throughput. There is substantial ongoing effort to use scRNA-seq measurements to identify the "cell types" that form components of a complex tissue, akin to ...
Shekhar, Karthik, Menon, Vilas
openaire +4 more sources
Hysteresis and bi-stability by an interplay of calcium oscillations and action potential firing
, 2006 Many cell types exhibit oscillatory activity, such as repetitive action potential firing due to the Hodgkin-Huxley dynamics of ion channels in the cell membrane or reveal intracellular inositol triphosphate (IP$_3$) mediated calcium oscillations (CaOs ...
A. P. R. Theuvenet +9 more
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