Results 81 to 90 of about 3,543,075 (195)

Distinct Transcriptomic Cell Types and Neural Circuits of the Subiculum and Prosubiculum along the Dorsal-Ventral Axis

Cell Reports, 2020
Summary: Subicular regions play important roles in spatial processing and many cognitive functions, and these are mainly attributed to the subiculum (Sub) rather than the prosubiculum (PS).
Song-Lin Ding, Zizhen Yao, Karla E. Hirokawa, Thuc Nghi Nguyen, Lucas T. Graybuck, Olivia Fong, Phillip Bohn, Kiet Ngo, Kimberly A. Smith, Christof Koch, John W. Phillips, Ed S. Lein, Julie A. Harris, Bosiljka Tasic, Hongkui Zeng   +14 more
doaj   +1 more source

Discovering cell types using manifold learning and enhanced visualization of single-cell RNA-Seq data

Scientific Reports, 2022
Identifying relevant disease modules such as target cell types is a significant step for studying diseases. High-throughput single-cell RNA-Seq (scRNA-seq) technologies have advanced in recent years, enabling researchers to investigate cells individually
Akram Vasighizaker, Saiteja Danda, Luis Rueda   +2 more
doaj   +1 more source

Single-Cell Transcriptomes Reveal a Complex Cellular Landscape in the Middle Ear and Differential Capacities for Acute Response to Infection. [PDF]

, 2020
Single-cell transcriptomics was used to profile cells of the normal murine middle ear. Clustering analysis of 6770 transcriptomes identified 17 cell clusters corresponding to distinct cell types: five epithelial, three stromal, three lymphocyte, two ...
Draf, Clara, Fisch, Kathleen M, Kurabi, Arwa, Nasamran, Chanond A, Pak, Kwang, Ryan, Allen F, Webster, Nicholas   +6 more
core  

Rate-dependency of action potential duration and refractoriness in isolated myocytes from the rabbit AV node and atrium [PDF]

, 2000
During atrial fibrillation, ventricular rate is determined by atrioventricular nodal (AVN) conduction, which in part is dependent upon the refractoriness of single AVN cells.
Andrew C. Rankin, Antony J. Workman, Anyukhovsky, Billette, Boyett, Cagin, Carmeliet, Dawodu, Delmar, Delmar, Denes, Duan, Fermini, Ferrier, Gibbs, Giles, Giles, Green, Hancox, Hoshino, Howarth, Isenberg, Jurkiewicz, Kaab, Kathleen A. Kane, Kukushkin, Li, Li, Meijler, Meijler, Mitcheson, Munk, Nakayama, Nattel, Nayebpour, Neher, Nilius, Petrecca, Rankin, Ravens, Shibata, Shigematsu, Tanaka, Vaughan-Williams, Wang, Wang, Wang, Wenckebach, Workman   +48 more
core   +1 more source

Whole-embryonic identification of maternal microchimeric cell types in mouse using single-cell RNA sequencing

Scientific Reports, 2022
Even though the mother and the fetus of placental mammals are immunologically non-self with respect to one other, mutual exchange of small numbers of cells between them is known to occur.
Kana Fujimoto, Akira Nakajima, Shohei Hori, Yumiko Tanaka, Yoshitaka Shirasaki, Sotaro Uemura, Naoki Irie   +6 more
doaj   +1 more source

A Universal Live Cell Barcoding-Platform for Multiplexed Human Single Cell Analysis. [PDF]

, 2018
Single-cell barcoding enables the combined processing and acquisition of multiple individual samples as one. This maximizes assay efficiency and eliminates technical variability in both sample preparation and analysis.
Bendall, Sean C, Hartmann, Felix J, Simonds, Erin F   +2 more
core  

Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. [PDF]

, 2018
Visual information is delivered to the brain by >40 types of retinal ganglion cells (RGCs). Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of each RGC type are restricted to specific sublaminae ...
Chen, Bin, Krishnaswamy, Arjun, Laboulaye, Mallory A, Liu, Jinyue, Pandey, Shristi, Reggiani, Jasmine DS, Rubenstein, John LR, Sanes, Joshua R   +7 more
core   +1 more source

Plant Single Cell Type Systems Biology

, 2016
The phenotype of a plant in response to a stress condition is the reflection of the molecular responses in different cell-types composing the plant. The multicellular complexity represents a challenge when accessing specific responses of each cell or cell type composing the plant.
Libault, Marc, Chen, Sixue
openaire   +3 more sources

Robust identification of perturbed cell types in single-cell RNA-seq data

Nature Communications
Single-cell transcriptomics has emerged as a powerful tool for understanding how different cells contribute to disease progression by identifying cell types that change across diseases or conditions.
Phillip B. Nicol, Danielle Paulson, Gege Qian, X. Shirley Liu, Rafael Irizarry, Avinash D. Sahu   +5 more
doaj   +1 more source

Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses. [PDF]

, 2019
Extracellular RNAs (exRNAs) can be released by numerous cell types in vitro, are often protected within vesicles, and can modify recipient cell function. To determine how the composition and cellular sources of exRNAs and the extracellular vesicles (EVs)
Ansel, K Mark, Chiou, Ni-Ting, Gray, Carleigh J, Happ, Hannah C, Hesse, Laura E, Mar, Darryl J, Pua, Heather H   +6 more
core   +1 more source