Results 121 to 130 of about 12,073,927 (302)

An intronic variant in TBX4 in a single family with variable and severe pulmonary manifestations. [PDF]

open access: yesNPJ Genom Med, 2023
Flanagan FO   +10 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Perkins family

open access: yes, 1890
Perkins family ...
Perkins family
core   +1 more source

FAMILY SYSTEM’S ROLE IN THE PSYCHOLOGICAL WELL-BEING OF THE CHILDREN

open access: yesKhyber Medical University Journal, 2017
OBJECTIVE: To find out the influence of single- and joint-family systems on psychological well-being of children. METHODS: This comparative study was conducted on 200 participants, including 100 (50 male & 50 female) from single-family system and 100 ...
Nighat Gul   +4 more
doaj  

Physicians' professionalism from the patients' perspective: a qualitative study at a single-family practice in Saudi Arabia. [PDF]

open access: yesBMC Med Ethics, 2023
AlFaris E   +9 more
europepmc   +1 more source

A Comparative Study on the Leisure Participation and Leisure Constraint of Single-Parent Family and Generally Family Household.

open access: yes, 2009
[[abstract]]1. Regular families? favorite leisure activities are reading the newspaper, listening to music, reading books and taking a walk respectively. The least favorite leisure activity was dancing. 2.
HSIEH SU-MI
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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