Results 131 to 140 of about 2,809,841 (250)

Single Health System Adherence to 2012 Cervical Cancer Screening Guidelines at Extremes of Age and Posthysterectomy. [PDF]

Obstet Gynecol, 2017
Teoh D, Isaksson Vogel R, Hultman G, Monu M, Downs L, Geller MA, Le C, Melton-Meaux G, Kulasingam S.   +8 more
europepmc   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Differences in pain regimens among nulliparous patients undergoing intrauterine device placement within a single health system. [PDF]

Am J Obstet Gynecol
Tsevat DG, Miller V, Hodges M, Mizelle C, Kessel J, Sauer G, Arora KS, Allison JH, Allison BA.   +8 more
europepmc   +1 more source

The Effect of a Statewide Mandatory Prescription Drug Monitoring Program on Opioid Prescribing by Emergency Medicine Providers Across 15 Hospitals in a Single Health System. [PDF]

J Pain, 2018
Suffoletto B, Lynch M, Pacella CB, Yealy DM, Callaway CW.   +4 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A multihospital, single health system validation of International Classification of Diseases, 10th Revision, Clinical Modification coding for status epilepticus in the United States. [PDF]

Epilepsia
MacKenzie M, Jette N, Johnson BJ, Agarwal P, Schreckinger C, Ferreira-Atuesta C, Townes S, Mathew B, Cohen A, Nirenberg S, Blank LJ.   +10 more
europepmc   +1 more source

Hepatitis C Within a Single Health System: Progression Along the Cascade to Cure Is Higher for Those With Substance Misuse When Linked to a Clinic With Embedded Support Services. [PDF]

Open Forum Infect Dis, 2018
Sherbuk JE, McManus KA, Rogawski McQuade ET, Knick T, Henry Z, Dillingham R.   +5 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effect of antecedent B-cell depletion therapy for patients hospitalized with COVID-19 within a single health system: a propensity score analysis. [PDF]

Sci Rep
Garneau WM, Wang K, Liang T, Xu Y, Gladstone DE, Avery RK, D'Alessio FR, Robinson ML, Sahetya SK, Garibaldi BT, Gebo KA, Dioverti MV.   +11 more
europepmc   +1 more source

Cost variation in a laparoscopic cholecystectomy and the association with outcomes across a single health system: implications for standardization and improved resource utilization. [PDF]

HPB (Oxford), 2015
Brauer DG, Hawkins WG, Strasberg SM, Brunt LM, Jaques DP, Mercurio NR, Hall BL, Fields RC.   +7 more
europepmc   +1 more source