Results 131 to 140 of about 6,089,213 (291)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Актуальные проблемы теоретической и клинической медицины, 2022 Overview and analytical article by Jainakbayev M.N. on the topic “Study of foreign experience in providing paid and free medical services and its using in the health system of Kazakhstan” provides an overview of effective tools and mechanisms for ...
М. Н. Джайнакбаев
doaj
A Retrospective Cross-Sectional Study of Severe Breakthrough SARS-CoV-2 Infection in the General Population Requiring Hospitalization Within a Single Health System. [PDF]
J Clin Med Res, 2022 Acharya R +5 more
europepmc +1 more source
"Toward True Health Care Reform: More Care, Less Insurance" [PDF]
The United States has the most expensive health care system in the world, yet its system produces inferior outcomes relative to those in other countries.
L. Randall Wray, Marshall Auerback
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Serviço e comunidade, vetores para a formação em saúde: o curso de medicina da Uniderp
Revista Brasileira de Educação MédicaEste trabalho registra o processo de concepção, implantação e implementação do Programa Interinstitucional de Interação de Ensino, Serviço, Comunidade (Pinesc), uma parceria entre a universidade e a Prefeitura Municipal de Campo Grande, visando à ...
Paulo Eduardo Cabral +6 more
doaj +1 more source
Type 2 diabetes mellitus burdens among adults with sickle cell disease: A 12-year single health system-based cohort analysis. [PDF]
EJHaem, 2021 Zhou J +6 more
europepmc +1 more source
Sensing viruses by mechanical tension of DNA in responsive hydrogels
, 2013 The rapid worldwide spread of severe viral infections, often involving novel modifications of viruses, poses major challenges to our health care systems. This means that tools that can efficiently and specifically diagnose viruses are much needed.
Cherstvy, Andrey G. +2 more
core +2 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source