Results 231 to 240 of about 8,190,383 (300)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Direct Measurement of Dissolved Gas Using a Tapered Single-Mode Silica Fiber. [PDF]

Sensors (Basel)
Sun P, Hu M, Zhu L, Zhang H, Lv J, Liu Y, Liang J, Wang Q.   +7 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

High Relative Humidity-Induced Growth of Perovskite Nanowires from Glass toward Single-Mode Photonic Nanolasers at Sub-100-nm Scale. [PDF]

Adv Sci (Weinh)
Wang Z, Li X, Chen C, Lou M, Wu J, Gao K, Li Z, Sun K, Li Z, Xiao Z, Li L, Wang P, Bai S, Qiu J, Tan D.   +14 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Photobleaching Effect on the Sensitivity Calibration at 638 nm of a Phosphorus-Doped Single-Mode Optical Fiber Dosimeter. [PDF]

Sensors (Basel)
Fricano F, Morana A, Roche M, Facchini A, Mélin G, Clément F, Balcon N, Mekki J, Marin E, Ouerdane Y, Boukenter A, Robin T, Girard S.   +12 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Modeling and simulation of amplified spontaneous emission in single-mode-pumped Cr²⁺:ZnSe bulk amplifiers with beam propagation and equivalent input-noise seeding. [PDF]

Appl Phys B
Nilsson J.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Experimental Study of White Light Interferometry in Mach-Zehnder Interferometers Based on Standard Single Mode Fiber. [PDF]

Sensors (Basel)
Cano-Perez JL, Gutiérrez-Gutiérrez J, Perezcampos-Mayoral C, Pérez-Campos EL, Pina-Canseco MDS, Tepech-Carrillo L, Vargas-Treviño M, Guerra-Hernández EI, Martínez-Helmes A, Estudillo-Ayala JM, Sierra-Hernández JM, Rojas-Laguna R.   +11 more
europepmc   +1 more source