Results 131 to 140 of about 310,423 (261)

Single-Molecule Imaging and Spectroscopy Enables Quantification of Location-Dependent Light-Matter Interactions on Nanoantennas. [PDF]

Small Sci
Lang L, Nooteboom S, Huijben TAPM, Mahajan S, Marie R, Zijlstra P, Fleischer M.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Profiling of Integrin Isoforms on Lung-Tropic Exosomes by Spectrally and Kinetically Multiplexed Single-Molecule Imaging. [PDF]

Adv Sci (Weinh)
Liu S, Wang H, Shentu Q, Yuan L, Tie J, Li L, Ai R, Ma B, Qi L, Jiang Y, Fang X.   +10 more
europepmc   +1 more source

Single-Molecule Imaging Reveals Differential AT1R Stoichiometry Change in Biased Signaling. [PDF]

Int J Mol Sci, 2023
Qin G, Xu J, Liang Y, Fang X.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

4polar3D single molecule imaging of 3D orientation in dense actin networks using ratiometric polarization splitting. [PDF]

Nat Commun
Senthil Kumar CS, Valades Cruz CA, Sison M, Vesga AG, Rey-Barroso J, Curcio V, Alemán-Castañeda LA, Alonso MA, Poincloux R, Mavrakis M, Brasselet S.   +10 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Heterogeneous template-dependent transcription dynamics of T7 RNAP revealed by single-molecule imaging. [PDF]

Proc Natl Acad Sci U S A
Zernia S, Deplazes-Lauber J, Huber J, Stigler J.   +3 more
europepmc   +1 more source

Live cell single-molecule imaging to study DNA repair in human cells. [PDF]

DNA Repair (Amst), 2023
Heyza JR, Mikhova M, Schmidt JC.
europepmc   +1 more source

Single-Molecule Imaging [PDF]

, 2013
openaire   +1 more source