Results 101 to 110 of about 2,268,593 (294)

Mechanical properties of branched actin filaments

open access: yes, 2015
Cells moving on a two dimensional substrate generate motion by polymerizing actin filament networks inside a flat membrane protrusion. New filaments are generated by branching off existing ones, giving rise to branched network structures.
Benetatos, Panayotis   +3 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The Effect of Migration on Earnings and Welfare Benefit Receipt [PDF]

open access: yes
This paper analyzes the outcomes of single mothers who move. I find that the earnings of single mother movers decline sharply relative to stayers in the years before moving.
Isaac C. Rischall
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Forecasting India’s Electricity Demand Using a Range of Probabilistic Methods

open access: yesEnergies, 2019
With serious energy poverty, especially concerning power shortages, the economic development of India has been severely restricted. To some extent, power exploitation can effectively alleviate the shortage of energy in India.
Yeqi An, Yulin Zhou, Rongrong Li
doaj   +1 more source

Forecasting intermittent demand [PDF]

open access: yes, 2006
Methods for forecasting intermittent demand are compared using a large data-set from the UK Royal Air Force (RAF). Several important results are found.
Duncan, L, Teunter, R H
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Perhitungan Peramalan Pengadaan Obat Menggunakan Metode Single Exponential Smoothing Dan Single Moving Average Pada Unit Farmamin Dinas Kesehatan Provinsi Jawa Tengah

open access: yesJOINS (Journal of Information System), 2017
Abstrak Ketidakstabilan jumlah setiap jenis obat yang disediakan oleh Dinas Kesehatan Provinsi Jawa Tengah untuk setiap Kabupaten/Kota dikarenakan masih dilakukan secara konvensional yaitu hanya dengan melakukan perhitungan manual dengan menjumlahkan
Lintang Mekar Tanjung, Amiq Fahmi
doaj  

Monitoring Process Mean and Variance with a Single Generally Weighted Moving Average Chart

open access: yesCommunications in Statistics - Theory and Methods, 2012
Two generally weighted moving average (GWMA) charts are usually used concurrently for a simultaneous monitoring of the process mean and process variance. In this article, we propose a new GWMA chart, called the Max-GWMA chart, which uses a single statistic for a simultaneous monitoring of the process mean and variance.
Teh, S. Y.   +2 more
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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