Results 1 to 10 of about 717,297 (383)

Electrophoretic Detection of Single-Nucleotide Polymorphisms [PDF]

BioTechniques, 2000
Single-nucleotide polymorphisms (SNPs) represent the most prevalent class of genetic markers available for linkage disequilibrium or cladistic analyses. PCR primers may be labeled with fluorescent dyes and used to rapidly and accurately differentiate among alleles that are defined by a single-nucleotide differences.
Deven R. See, Vladimir Kanazin, Hope Talbert, Tom Blake   +3 more
openalex   +5 more sources

Genetic epidemiology of single-nucleotide polymorphisms [PDF]

Proceedings of the National Academy of Sciences, 1999
On the causal hypothesis, most genetic determinants of disease are single-nucleotide polymorphisms (SNPs) that are likely to be selected as markers for positional cloning. On the proximity hypothesis, most disease determinants will not be included among markers but may be detected through linkage disequilibrium with other SNPs.
Andrew Collins, Christine Lonjou, Newton E. Morton   +2 more
openalex   +5 more sources

Detection of Single-Nucleotide Polymorphism

BioTechniques, 1998
Weikuan Gu, Gustavo D. Aguirre, Kunal Ray   +2 more
doaj   +4 more sources

Single-Nucleotide Polymorphism

Encyclopedia of Autism Spectrum Disorders, 2020
Montana T. Morris, A. Jeremy Willsey
openaire   +3 more sources

TMPRSS2 gene, single nucleotide polymorphism rs8134378, single nucleotide polymorphism rs12329760.

Syrian Journal for Science and Innovation, 2023
Since the spread of the COVID-19 pandemic, there has been a variation in the prevalence rates of the coronavirus that causes the disease, the distribution of moderate and severe symptoms, and death rates, among different populations.
Majd Aljamali , Lama Youssef
doaj   +1 more source

A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation

Science, 2022
Establishing causal links between inherited polymorphisms and cancer risk is challenging. Here, we focus on the single-nucleotide polymorphism rs55705857, which confers a sixfold greater risk of isocitrate dehydrogenase (IDH)–mutant low-grade glioma (LGG)
C. Yanchus, K. Drucker, T. Kollmeyer, R. Tsai, M. Liang, L. Jiang, J. Pawling, A. Ali, P. Decker, M. Kosel, A. Panda, A. Malik, K. Al-Zahrani, J. Hernandez, M. Ahmed, S. Loganathan, D. Trcka, A. Michaelraj, J. Fortin, P. Mazrooei, L. Zhou, A. Elia, M. Lupien, H. He, L. Wang, A. Abyzov, J. Dennis, M. Wilson, J. Wrana, D. Lachance, M. Wrensch, J. Wienck, L. Pennacchio, D. Dickel, A. Visel, M. Taylor, G. Zadeh, P. Dirks, J. E. Eckel Passow, T. Mak, E. Kvon, R. Jenkins, D. Schramek   +42 more
semanticscholar   +1 more source

Detection of Single Nucleotide Polymorphisms [PDF]

Current Issues in Molecular Biology, 2003
Single nucleotide polymorphism (SNP) detection technologies are used to scan for new polymorphisms and to determine the allele(s) of a known polymorphism in target sequences. SNP detection technologies have evolved from labor intensive, time consuming, and expensive processes to some of the most highly automated, efficient, and relatively inexpensive ...
Kwok, Pui-Yan, Chen, Xiangning
openaire   +3 more sources

Predicting late-stage age-related macular degeneration by integrating marginally weak SNPs in GWA studies

Frontiers in Genetics, 2023
Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative disease and the leading cause of blindness in developed countries.
Xueping Zhou, Jipeng Zhang, Ying Ding, Heng Huang, Yanming Li, Wei Chen   +5 more
doaj   +1 more source

Single-Nucleotide Polymorphisms in Soybean [PDF]

Genetics, 2003
Abstract Single-nucleotide polymorphisms (SNPs) provide an abundant source of DNA polymorphisms in a number of eukaryotic species. Information on the frequency, nature, and distribution of SNPs in plant genomes is limited. Thus, our objectives were (1) to determine SNP frequency in coding and noncoding soybean (Glycine max L.
Perry B. Cregan, David L. Hyten, Qijian Song, Qijian Song, S. M. Hyatt, Lakshmi K. Matukumalli, Lakshmi K. Matukumalli, Edward W. Fickus, Youlin Zhu, Youlin Zhu, Nevin D. Young, Dirk Grimm, C.P. Van Tassell   +12 more
openaire   +3 more sources

Recent Progress in Single-Nucleotide Polymorphism Biosensors

Biosensors, 2023
Single-nucleotide polymorphisms (SNPs), the most common form of genetic variation in the human genome, are the main cause of individual differences. Furthermore, such attractive genetic markers are emerging as important hallmarks in clinical diagnosis ...
Kaimin Wu, Feizhi Kong, Jingjing Zhang, Ying Tang, Yao Chen, Long Chao, Libo Nie, Zhao Huang   +7 more
doaj   +1 more source