Results 11 to 20 of about 265,800 (250)

Development and validation of a dual-purpose 60K single nucleotide polymorphism chip for simultaneous genotyping of chicken and duck [PDF]

Animal Bioscience
Objective Chickens and ducks represent the most important poultry species within the livestock industry. However, the availability of single nucleotide polymorphism (SNP) chips for these species is limited, and development of separate chips for each ...
Jinhyeong Kim, Eunjin Cho, Minjun Kim, Jaewon Kim, Dongwon Seo, Jung-Woo Choi, Won-Hyong Chung, Yeongkuk Kim, Hyojun Choo, Jun Heon Lee   +9 more
doaj   +2 more sources

Heterogeneous lengths of copy number mutations in human coagulopathy revealed by genome-wide high-density SNP array

Haematologica, 2012
Background The recent advent of genome-wide molecular platforms has facilitated our understanding of the human genome and disease, particularly copy number aberrations.
Hee-Jin Kim, Duk-Kyung Kim, Ki-Young Yoo, Chur-Woo You, Jong-Ha Yoo, Ki-O Lee, In-Ae Park, Hae-Sun Choung, Hee-Jung Kim, Min-Jung Song, Sun-Hee Kim   +10 more
doaj   +1 more source

Bulk segregant analysis using single nucleotide polymorphism microarrays. [PDF]

PLoS ONE, 2011
Bulk segregant analysis (BSA) using microarrays, and extreme array mapping (XAM) have recently been used to rapidly identify genomic regions associated with phenotypes in multiple species.
Anthony Becker, Dai-Yin Chao, Xu Zhang, David E Salt, Ivan Baxter   +4 more
doaj   +1 more source

Construction and analysis of single nucleotide polymorphism–single nucleotide polymorphism interaction networks

IET Systems Biology, 2013
The study of gene regulatory network and protein–protein interaction network is believed to be fundamental to the understanding of molecular processes and functions in systems biology. In this study, the authors are interested in single nucleotide polymorphism (SNP) level and construct SNP–SNP interaction network to understand genetic characters and ...
Yang, Liu, Xutao, Li, Zhiping, Liu, Luonan, Chen, Michael K, Ng   +4 more
openaire   +3 more sources

p53 codon 72 polymorphism in Taiwanese breast cancer patients

Kaohsiung Journal of Medical Sciences, 2013
There are clear discrepancies between ethnicity and geographic area regarding the peak age incidence and mortality of breast cancer. Underlying variances include genetic, environmental, and socioeconomic factors.
Fang-Ming Chen, Fu Ou-Yang, Sheau-Fang Yang, Eing-Mei Tsai, Ming-Feng Hou   +4 more
doaj   +1 more source

Single Nucleotide Polymorphism Clustering in Systemic Autoimmune Diseases. [PDF]

PLoS ONE, 2016
Systemic Autoimmune Diseases, a group of chronic inflammatory conditions, have variable symptoms and difficult diagnosis. In order to reclassify them based on genetic markers rather than clinical criteria, we performed clustering of Single Nucleotide ...
Thomas Charlon, Manuel Martínez-Bueno, Lara Bossini-Castillo, F David Carmona, Alessandro Di Cara, Jérôme Wojcik, Sviatoslav Voloshynovskiy, Javier Martín, Marta E Alarcón-Riquelme   +8 more
doaj   +1 more source

Strong association of interleukin-6 −174G/C promoter single nucleotide polymorphism with a decreased risk of colorectal cancer in ethnic Kashmiri population: A case control study

Tumor Biology, 2017
Chronic inflammation increases the risk of development of various cancers, including colorectal cancer. Interleukin-6 has been described as a key regulator of colorectal cancer development and is important in the process of colorectal tumorigenesis ...
Mujeeb Zafar Banday, Henah Mehraj Balkhi, Aga Syed Sameer, Nissar A Chowdri, Ehtishamul Haq   +4 more
doaj   +1 more source

Lack of Association Between Toll-like Receptor 2 Polymorphisms (R753Q and A-16934T) and Atopic Dermatitis in Children from Thrace Region of Turkey

Balkan Medical Journal, 2017
Background: Atopic dermatitis is the most common chronic inflammatory skin disease. A complex interaction of both genetic and environmental factors is thought to contribute to the disease. Aims: To evaluate whether single nucleotide polymorphisms in the
Ceren Can, Mehtap Yazıcıoğlu, Hakan Gürkan, Hilmi Tozkır, Adnan Görgülü, Necdet Hilmi Süt   +5 more
doaj   +1 more source

Superoxide dismutase coding of gene polymorphisms associated with susceptibility to Parkinson’s disease [PDF]

Journal of Integrative Neuroscience, 2019
Oxidative stress linked to the etiology of Parkinson’s disease, which is characterized by chronic and progressive neurodegeneration of dopamine neurons.
Chunlei Liu, Jinju Fang, Wenke Liu
doaj   +1 more source

ABL single nucleotide polymorphisms may masquerade as BCR-ABL mutations associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukemia

Haematologica, 2008
The BCR-ABL K247R change is based on a rare single nucleotide polymorphism occurring likewise in healthy controls and non-hematologic cell types. Despite its juxtaposition to the P-loop, functional analysis showed no alteration compared to non-mutated ...
Thomas Ernst, Jana Hoffmann, Philipp Erben, Benjamin Hanfstein, Armin Leitner, Rüdiger Hehlmann, Andreas Hochhaus, Martin C. Müller   +7 more
doaj   +1 more source