Results 191 to 200 of about 715,579 (403)
A single nucleotide polymorphism in exon 1 of cytotoxic T-lymphocyte-associated-4 (CTLA-4) is not associated with rheumatoid arthritis [PDF]
, 2000 Anne Barton +5 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling +7 more
wiley +1 more source
Genomic structure and multiple single-nucleotide polymorphisms (SNPs) of the thiopurine S-methyltransferase (TPMT) gene [PDF]
, 2000 Toyokazu Seki +2 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica +4 more
wiley +1 more source
Association between single nucleotide polymorphisms in the hMSH3 gene and sporadic colon cancer with microsatellite instability [PDF]
, 2000 Hideo Orimo +5 more
openalex +1 more source
Brief introduction in phenotypic and genetic differences of C57BL/6 and BALB/c mice substrains
Animal Models and Experimental Medicine, EarlyView.This article briefly reviews the origin, differentiation, and phenotypic and genetic differences between the C57BL/6 and BALB/c mouse substrains. Abstract Experimental mice play a critical role in biomedical research. The phenotype and application of different substrains vary due to genetic differentiation and variation.
Lan Zhao, Jie Wei, Bingfei Yue
wiley +1 more source
Allelic Discrimination for Single Nucleotide Polymorphisms in the Human Scavenger Receptor Class B Type 1 Gene Locus Using Fluorescent Probes [PDF]
, 2000 D Osgood-McWeeney +2 more
openalex +1 more source
Paternity testing for crab‐eating macaques and rhesus macaques using microsatellite markers
Animal Models and Experimental Medicine, EarlyView.In our study, a total of 143 crab‐eating macaques and 52 rhesus macaques were collected. Their blood was collected and DNA was extracted. Polymerase Chain Reaction amplification and capillary electrophoresis detected the microsatellite markers. If the same genotype could be found in all microsatellite markers in the suspected parents, they were ...
Yiming Yuan +10 more
wiley +1 more source