International Journal of Cancer, EarlyView.Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia +4 more
wiley +1 more source
Estimating the Abundance of a Cryptic, Endangered Marsupial, Mala (<i>Lagorchestes hirsutus</i>) Using Microsatellite and Single Nucleotide Polymorphism Genotyping Panels. [PDF]
Ecol EvolCummins D +4 more
europepmc +1 more source
Clinical Relevance of BACH1 Expression in Non–Small Cell Lung Cancer
International Journal of Cancer, EarlyView.ABSTRACT BTB and CNC homolog 1 (BACH1) is a redox‐sensitive transcription factor implicated in tumor progression, metabolic reprogramming, and therapy resistance in several cancers. However, its prognostic significance and role in therapy resistance in non–small cell lung cancer (NSCLC) remain unclear.
Jing Liu +7 more
wiley +1 more source
High-density single nucleotide polymorphism markers analysis reveals the genetic diversity and population structure in tropical highland maize (Zea mays L.) inbred lines. [PDF]
PLoS OneGebre WT +3 more
europepmc +1 more source
Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in Sweden
International Journal of Cancer, EarlyView.ABSTRACT Available epidemiological evidence shows that many cancers share familial risks, and this is increasingly confirmed by data on shared pathogenic germline gene variants between cancers. We decided to harness the world's largest resource on familial cancer to assess discordant familial risks for female breast (BC), prostate (PC), colorectal (CRC)
Frantisek Zitricky +5 more
wiley +1 more source
Neonatal cytogenetic validation demonstrates high accuracy of single-nucleotide polymorphism-based non-invasive prenatal testing: a 4466-case single-center study. [PDF]
J Hum GenetUchida S +4 more
europepmc +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
Correction: Genetic diversity and population structure analyses of tropical maize inbred lines using Single Nucleotide Polymorphism markers. [PDF]
PLoS OneGunundu R, Shimelis H, Tesfamariam SA.
europepmc +1 more source
iMetaMed, EarlyView.Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang +6 more
wiley +1 more source