Results 191 to 200 of about 274,651 (250)

A case-control study on the individualized use of opioid analgesics based on single-nucleotide polymorphism. [PDF]

Front Pharmacol
Yang J, Zheng L, Zheng F, Zhou SH, Sun LW, Song C.   +5 more
europepmc   +1 more source

Polymorphic STRs represent unique genetic signals beyond SNPs associated with climate adaptation in Marchantia polymorpha

iMetaOmics, EarlyView.
Natural populations of Marchantia polymorpha sampled across contrasting climatic regions show clear geographic differentiation between Europe and Japan based on polymorphic short tandem repeat (STR) variation. Genome‐wide association (GWAS) analyses identified pSTR loci whose repeat‐length variation tracks temperature‐related WorldClim variables.
Shuangyang Wu, Shenghan Gao, Sen Wang, Martin Lascoux, Hao Yu   +4 more
wiley   +1 more source

Integration of Point-of-Care Technology in the Decoding Process of Single Nucleotide Polymorphism for Healthcare Application ^†. [PDF]

Micromachines (Basel)
Trinh TND, Nguyen HA, Thi NPA, Ho TXT, Trinh KTL, Tran NKS.   +5 more
europepmc   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Association Between Single-Nucleotide Polymorphism and Trastuzumab Deruxtecan-Induced Interstitial Lung Disease in Breast Cancer Using the Japonica Array NEO. [PDF]

Cancers (Basel)
Fujiwara S, Saito N, Yasukawa M, Narita A, Sakurai-Yageta M, Sato S, Yamashita T, Hoshino D.   +7 more
europepmc   +1 more source

Deciphering transcriptome complexity via long‐read sequencing

iMeta, EarlyView.
Long‐read sequencing is transforming transcriptomics from gene‐level quantification to isoform‐resolved interpretation by directly resolving full‐length transcript structures, transcription in repetitive regions, and linked molecular features. This review provides an end‐to‐end roadmap covering sequencing platforms, library preparation strategies ...
Chuwen Xu, Jia Li, Chenxi Yin, Keying Li, Tian Wang, Shiwen Gao, Yue Yu, Cheng Chang, Ye Wang, Guoqing Tong, Liang Gong, Wen Hu, Guoliang Chai, Yilai Han, Qian Qin, Suoqin Jin, Xiufen Zou, Bo Li, Tianyuan Zhang, Ana Conesa, Yunhao Wang, Dingjie Wang   +21 more
wiley   +1 more source

Whole-genome paternal uniparental disomy identified through prenatal single-nucleotide polymorphism-based cell-free DNA screening. [PDF]

Ultrasound Obstet Gynecol
Benn P, Hashimoto K, Souter V, Dhamankar R, Xu W, Kijacic D.   +5 more
europepmc   +1 more source

Clinical application of single nucleotide polymorphism array in prenatal diagnosis: Experience with 8753 samples. [PDF]

PLoS One
Wen L, Zhang Y, Zhang W, Mao A, Li X.
europepmc   +1 more source

Exploring the presence of the GPR126 single nucleotide polymorphism (rs536714306) in periodontal patients of European ancestry. [PDF]

BMC Res Notes
Chatzopoulou E, Fanourakis G, Papanikolaou N, Chatzistamou I, Dereka X, Vastardis H.   +5 more
europepmc   +1 more source

Single Nucleotide Polymorphism Microarray Analysis Unveils Copy-Number Abnormalities and Genetic Heterogeneity in Malaysian Childhood B-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]

Mol Genet Genomic Med
Mohd Dali NS, Aziz NA, Zulkifle MF, Zamri DA, Kamaluddin NR, Yeoh SL, Ho BL, Din ND, Ab Ghani AS, Wan Hassan WAH, Zakaria Z, Esa E, Mat Yusoff Y.   +12 more
europepmc   +1 more source