Results 241 to 250 of about 479,118 (340)

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Gut‐microbiota‐brain Axis and post‐traumatic epilepsy

Epilepsia Open, EarlyView.
Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley   +1 more source

Role of single-nucleotide polymorphism microarray in the classification of BAP1-inactivated melanocytic tumours. [PDF]

Histopathology
Durgin JS, Zoumberos NA, Novice T, Fullen DR, Hristov AC, Lowe L, Patel RM, Harms PW, Andea AA, Bresler SC.   +9 more
europepmc   +1 more source

Identification of single nucleotide polymorphisms (SNPs) in the transcriptome of sugarcane variety Co 86032 exposed to oxidative stress.

, 2019
S. Gayathri, M. Arockiyajainmary, R M Shalini, M. R. Vannish, A. Selvı, R. Manimekalai   +5 more
openalex   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

Association Between Single-Nucleotide Polymorphism rs2287886 of <i>CD209</i> Gene and Clinical Severity of COVID-19 in Unvaccinated Brazilian Patients. [PDF]

Genes (Basel)
Galisa SLG, Silva RRCD, Aguiar MC, Sá MVBO, Melo JVO, Pereira GVN, Silva JRLE, Paiva BLX, Henrique AGDS, Carmo RFD, de Souza CDF, Armstrong ADC, Oliveira PRS, Silva Vasconcelos LR.   +13 more
europepmc   +1 more source

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

A <i>POLR1D</i>-regulating single-nucleotide polymorphism as a predictive marker candidate for platinum-based chemotherapy in gastrointestinal cancers. [PDF]

Ther Adv Med Oncol
Mori T, Ueno K, Nagasaki M, Matsuda K, BioBank Japan Project.   +4 more
europepmc   +1 more source

Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer

, 2011
Shanbeh Zienolddiny, Vidar Skaug
openalex   +1 more source

Assessing the causal relationship between the plasma proteome and epilepsy: A Mendelian randomization study

Epilepsia Open, EarlyView.
Abstract Objective Understanding the role of plasma proteins in the pathophysiology of epilepsy is crucial for uncovering novel biological mechanisms and therapeutic targets. Mendelian randomization (MR) provides a valuable tool for dissecting potentially causal associations between circulating proteins and disease risk.
Jingfeng Fu, Wei Wu, Shangren Shen
wiley   +1 more source