UGT2B15 single nucleotide polymorphism reduces dabigatran acylglucuronide formation in humans. [PDF]
Park JW+5 more
europepmc +1 more source
Allele-specific binding of the ubiquitous transcription factor OCT-1 to the functional single nucleotide polymorphism (SNP) sites in the tumor necrosis factor-alpha gene (TNFA) promoter [PDF]
Hirohiko Hohjoh, Katsushi Tokunaga
openalex +1 more source
B cells and systemic sclerosis interstitial lung disease
Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman+2 more
wiley +1 more source
A single nucleotide polymorphism produces different transcription profiles in <i>Campylobacter jejuni's cysM</i>. [PDF]
Gunther Iv NW+6 more
europepmc +1 more source
The human XPG gene: gene architecture, alternative splicing and single nucleotide polymorphisms [PDF]
Steffen Emmert
openalex +1 more source
Cattle Genomics: Aurochs Admixture in East Asia
Animal Research and One Health, EarlyView.
James A. Ward, David E. MacHugh
wiley +1 more source
Abstract Aims Observational studies have suggested associations between heart failure (HF), frailty and poisoning by narcotics and psychodysleptics (PNP). However, establishing causal relationships has been challenging. This study used a two‐sample Mendelian randomization (MR) approach to investigate the genetically proxied causality between HF ...
Bing Wang+3 more
wiley +1 more source
Catalog of 258 single-nucleotide polymorphisms (SNPs) in genes encoding three organic anion transporters, three organic anion-transporting polypeptides, and three NADH:ubiquinone oxidoreductase flavoproteins [PDF]
Aritoshi Iida+8 more
openalex +1 more source
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza+26 more
wiley +1 more source