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Empirical Bayes analysis of single nucleotide polymorphisms [PDF]
BMC Bioinformatics, 2008 Background An important goal of whole-genome studies concerned with single nucleotide polymorphisms (SNPs) is the identification of SNPs associated with a covariate of interest such as the case-control status or the type of cancer.
Ickstadt Katja, Schwender Holger
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The influence of genetic polymorphisms on the toxicity of platinum-based chemotherapy in the treatment of non-small cell lung cancer [PDF]
Medicinski Podmladak, 2021 Lung cancer remains one of the most frequent and the deadliest of malignant diseases throughout the world. Target and immune therapy have revolutionalized the treatment of this disease, but platinum-based chemotherapy still has a place in the treatment ...
Spasić Jelena +2 more
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Association between Single Nucleotide Polymorphisms of the Major Histocompatibility Complex Class II Gene and Newcastle Disease Virus Titre and Body Weight in Leung Hang Khao Chickens [PDF]
Asian-Australasian Journal of Animal Sciences, 2016 The aim of the present study was to investigate the effect of single nucleotide polymorphisms in the major histocompatibility complex (MHC) class II gene on resistance to Newcastle disease virus and body weight of the Thai indigenous chicken, Leung Hang ...
A. Molee +4 more
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Association between SORL1 polymorphisms and the risk of Alzheimer's disease [PDF]
Journal of Integrative Neuroscience, 2018 A meta-analysis was performed to identify empirical data assessing the effects of a single nucleotide polymorphisms of sortilin-related receptor on Alzheimer's disease based on 14 studies involving 37941 cases and 49727 control studies. Analysis showed, (
Lele Cong, Xiangyi Kong, Jing Wang, Jianshi Du, Zhongxin Xu, Yanan Xu, Qing Zhao
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PLoS Computational Biology, 2020 Single nucleotide polymorphisms are widely associated with disease, but the ways in which they cause altered phenotypes are often unclear, especially when they appear in non-coding regions. One way in which non-coding polymorphisms could cause disease is
Elan Shatoff, Ralf Bundschuh
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Analysis of PRM1 and PRM2 Polymorphisms in Iranian Infertile Men with Idiopathic Teratozoospermia [PDF]
International Journal of Fertility and Sterility, 2019 Single nucleotide polymorphisms (SNPs) in a number of genes involved in sperm maturation are considered as one of the main factors for male infertility.
Fatemeh Dehghanpour +5 more
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Vitamin D and Vitamin D Receptor FokI, ApaI, and BsmI Gene Polymorphisms and their Relation with the Risk of Breast Carcinoma: A Case-control Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Breast cancer stands as the leading cause of mortality among women in developing nations. The potential role of Vitamin D in mitigating the incidence of breast cancer is thought to stem from its ability to impede cell proliferation by ...
Ashok Kumar Dogra +3 more
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Medical Journal of Babylon, 2023 Backgrounds: Breastfeeding provides a large group of functional components that improve the infant’s health and development. additionally, the impact of human milk and genetic variants on complicated outcomes has also been the subject of several gene ...
Shaimaa Thabit Salih, Ban Sahib Diab
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Single nucleotide polymorphisms and periodontitis
Dentistry and Medical Research, 2014 The susceptibility to various diseases is studied with association to genetic polymorphisms. Among these polymorphisms, single-nucleotide polymorphisms (SNPs) are very common throughout the genome.
Ramalingam Karthikeyan +5 more
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Frontiers in Genetics, 2023 Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative disease and the leading cause of blindness in developed countries.
Xueping Zhou +5 more
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