Results 141 to 150 of about 286,600 (201)

Single Nucleotide Polymorphisms

2006
The identification of DNA variation or gene mutations, which contributes to or determines a disease, has been a major research focus, as it describes the underlying inherited disease components. With the human genome being sequenced, the reference sequence is now at hand, facilitating the systematic identification of DNA variation and its subsequent ...
Ulrich Broeckel, Martin J. Hessner
  +7 more sources

Single-Nucleotide Polymorphism Mapping

2006
Single-nucleotide polymorphism (SNP) mapping is the easiest and most reliable way to map genes in Caenorhabditis elegans. SNPs are extremely dense and usually have no associated phenotype, making them ideal markers for mapping. SNP mapping has three steps.
M Wayne, Davis, Marc, Hammarlund
openaire   +2 more sources

Risk Prediction of Prostate Cancer with Single Nucleotide Polymorphisms and Prostate Specific Antigen

Journal of Urology, 2019
Purpose: Combined information on single nucleotide polymorphisms and prostate specific antigen offers opportunities to improve the performance of screening by risk stratification. We aimed to predict the risk of prostate cancer based on prostate specific
Sam Li-Sheng Chen, Jean Ching-Yuan Fann, C. Sipeky, Teng-Kai Yang, S. Yueh-Hsia Chiu, Amy Ming-Fang Yen, Virpi H. Laitinen, T. Tammela, U. Stenman, A. Auvinen, J. Schleutker, Hsiu-Hsi Chen   +11 more
semanticscholar   +1 more source

Polymorphism and single nucleotide polymorphisms ( SNP s)

BJU International, 2013
Greg Shaw
openaire   +3 more sources

Hypertension and single nucleotide polymorphisms

Current Hypertension Reports, 2000
Hypertension is a common, complex disease phenotype that has been intensively studied to identify susceptibility loci in humans. Candidate genes continue to be uncovered via genetic analysis in model organisms through linkage analysis with families and/or sib-pairs and through association studies using sequence variants in genes that play a role in key
M J, Rieder, D A, Nickerson
openaire   +2 more sources

single nucleotide polymorphism

2009
(SNP, pronounced “snips”) variation at just a single base of a four-bases (syn. nucleotides) long codon; it is assumed that SNPs predispose individuals to develop certain diseases but also to respond or not to certain drugs; → see also genom, pharmacogenetics.
openaire   +1 more source

Multiplex Single Nucleotide Polymorphism Analyses

2016
Quantitative polymerase chain reaction (qPCR) is a routinely used method for detection and quantitation of gene expression in real time. This is achieved through the incorporation and measurement of fluorescent reporter probes in the amplified cDNA strands, since the fluorescent signals increase as the reaction progresses.
Steve F C, Hawkins, Paul C, Guest
openaire   +2 more sources

Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome.

Science, 1998
David G. Wang, Jian-Bing Fan, C. Siao, Anthony Berno, Peter Young, R. Sapolsky, G. Ghandour, Nancy Perkins, E. Winchester, Jessica B. Spencer, L. Kruglyak, Lincoln Stein, L. Hsie, T. Topaloglou, E. Hubbell, Elizabeth Robinson, Mike Mittmann, M. S. Morris, Naiping Shen, D. Kilburn, J. Rioux, C. Nusbaum, S. Rozen, T. Hudson, R. Lipshutz, M. Chee, E. Lander   +26 more
semanticscholar   +1 more source

Single Nucleotide Polymorphisms

2023
openaire   +1 more source

Single nucleotide polymorphisms in clinics: Fantasy or reality for cancer?*

Critical reviews in clinical laboratory sciences, 2015
Srilakshmi Srinivasan, J. Clements, J. Batra   +2 more
semanticscholar   +1 more source