This study investigates how living in single-parent families during childhood influences tertiary education attainment, exploring the mechanisms involved, their heterogeneity by parental socioeconomic status and their variation over time.
Manuel Mejías-Leiva +1 more
doaj +1 more source
Analyzing Time Use by Occupation Area between Weekdays and Weekends by Gender of Parents in Single-Parent Families. [PDF]
Jang WH, Bang JH.
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Time usage analysis and satisfaction comparison by occupational area according to the sex of single-parent families. [PDF]
Jang WH, Jang JS, Bang JH.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
KEMANDIRIAN WANITA SINGLE PARENT DALAM MENDIDIK ANAK (Studi Kasus Di Desa Pakang, Andong, Boyolali)
The research aims are: 1. to describe the women independency of being single parent to educate their children at pakang village, Andong, Boyolali; 2.
Sumiyatun Sumiyatun, Achmad Muhibbin
doaj
Experiences of single-parent children in the current Indian context. [PDF]
Sangeet O, Singh S.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Risk perceptions of individuals living in single-parent households during the COVID-19 crisis: examining the mediating and moderating role of income. [PDF]
Liedl B +3 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source

