Results 81 to 90 of about 6,315,325 (309)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Della Parent

, 1990
Interview with Della Parent (nee Leveque, 1903-1998) of Nakusp, formerly of Comaplix, conducted by Milton Parent in Nakusp, British Columbia, January ...

core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

KETERLIBATAN PENGASUHAN AYAH SEBAGAI ORANG TUA TUNGGAL DENGAN ANAK PEREMPUANNYA SETELAH TERJADINYA PERCERAIAN (STUDI KASUS KOMUNIKASI ANTARPRIBADI DI DESA KWANGSAN, KECAMATAN JUMAPOLO)

Komuniti, 2017
Being a single parent is not easy especially for father, and caring for his girls are still under age of 12 years old. Beside for suffice the needs of the family of an themselves a father is a single parent should parenting is independent. The purpose of
Denny Astuti
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Della Parent (about Comaplix)

, 1995
Interview with Della Parent (nee Leveque, 1903-1998) of Nakusp, formerly of Comaplix, about the ghost town of Comaplix, conducted by Milton Parent in Nakusp, British Columbia, December ...

core  

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Edith Barrow, Bessie Vaughan and Della and Joseph Parent

, 1971
Interview with Edith Barrow (nee Pratt, 1908-2001), Della Parent (nee Leveque, 1903-1998), Joseph Parent (1898-1972), all of Nakusp, and Bessie Vaughan (nee McWhirter, 1906-1992), formerly of Nakusp, conducted by Milton Parent at Milton Parent's' home in

core  

Single-Parent Adolescents' Perceptions of Future Marriage and Family Expectations: A Qualitative Inquiry

İçtimaiyat
In recent years, as in many other countries, the number of single-parent families has been rapidly increasing in our country as well. Along with this increase, there is a growing need for qualitative research to understand better single-parent families ...
Merve Şahbaz, Demet Akarçay Ulutaş
doaj   +1 more source